Results 71 to 80 of about 162,660 (354)

Comparison between superior vena cava ablation in addition to pulmonary vein isolation and standard pulmonary vein isolation in patients with paroxysmal atrial fibrillation with the cryoballoon technique

Journal of interventional cardiac electrophysiology, 2021
Paroxysmal atrial fibrillation (PAF) can be triggered by non-pulmonary vein foci, like the superior vena cava (SVC). The latter is correlated with improved result in terms of freedom from atrial tachycardias (ATs), when electrical isolation of this ...
I. Overeinder, T. Osório, Paul-Adrian Călburean, A. Bisignani, G. Bala, J. Sieira, Erwin Ströker, Maysam Al Houssari, Joerelle Mojica, Serge Boveda, G. Paparella, P. Brugada, C. de Asmundis, G. Chierchia   +13 more
semanticscholar   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Mechanical function of left atrium and pulmonary vein sleeves before and after their antrum isolation

Medicina, 2014
Background and objective: Pulmonary vein (PV) sleeves are established as the main substrate taking part in the mechanisms of atrial fibrillation (AF) initiation.
Sergey Mamchur, Irina Mamchur, Egor Khomenko, Alexander Kokov, Nikita Bokhan, Diana Sherbinina   +5 more
doaj   +1 more source

Maintenance of low inflammation level by the ZFHX3 SNP rs2106261 minor allele contributes to reduced atrial fibrillation recurrence after pulmonary vein isolation. [PDF]

PLoS ONE, 2018
INTRODUCTION:The single nucleotide polymorphism (SNP) rs2106261 in the transcription factor gene ZFHX3 (16q22), a major regulator of inflammation, has been reported linking to atrial fibrillation (AF) by genome-wide association studies.
Shunsuke Tomomori, Yukiko Nakano, Hidenori Ochi, Yuko Onohara, Akinori Sairaku, Takehito Tokuyama, Chikaaki Motoda, Hiroya Matsumura, Michitaka Amioka, Naoya Hironobe, Yousaku Ookubo, Shou Okamura, Hiroshi Kawazoe, Kazuaki Chayama, Yasuki Kihara   +14 more
doaj   +1 more source

Association of the left common ostium with clinical outcome after pulmonary vein isolation in atrial fibrillation

Indian Pacing and Electrophysiology Journal, 2021
Introduction: Electrical pulmonary vein isolation (PVI) is used for the invasive treatment of atrial fibrillation (AF). However, despite the procedure’s technical evolution, the rate of AF recurrence due to electrical reconnection of the PVs is high. The
Rafael M. Ronsoni, Tiago L. Silvestrini, Vidal Essebag, Renato D. Lopes, Marco Aurélio Lumertz Saffi, Tiago Luiz Luz Leiria   +5 more
doaj   +1 more source

p22phox C242T Single-Nucleotide Polymorphism Inhibits Inflammatory Oxidative Damage to Endothelial Cells and Vessels. [PDF]

, 2016
BACKGROUND: The NADPH oxidase, by generating reactive oxygen species, is involved in the pathophysiology of many cardiovascular diseases and represents a therapeutic target for the development of novel drugs.
Brooks, G, Fan, LM, Ghazaly, MM, Howlin, B, Krönke, M, Li, J-M, Meijles, DN   +6 more
core   +1 more source

VARIPULSE: A step‐by‐step guide to pulmonary vein isolation

Cardiovascular Electrophysiology
The VARIPULSE™ variable‐loop circular catheter (VLCC) is a bidirectional, multielectrode catheter that can perform electrophysiological mapping and deliver pulsed field energy through the TRUPULSE™ Generator for the treatment of atrial fibrillation. This
Devi G. Nair, T. Gomez, T. D. De Potter
semanticscholar   +1 more source

Standardized pulmonary vein isolation workflow to enclose veins with contiguous lesions: the multicentre VISTAX trial.

Europace, 2020
AIMS To evaluate the safety and effectiveness of pulmonary vein isolation in paroxysmal atrial fibrillation (PAF) using a standardized workflow aiming to enclose the veins with contiguous and optimized radiofrequency lesions.
M. Duytschaever, J. Vijgen, T. D. De Potter, D. Scherr, H. Van Herendael, S. Knecht, R. Kobza, B. Berte, N. Sandgaard, J. Albenque, G. Széplaki, Y. Stevenhagen, P. Taghji, M. Wright, N. Macours, D. Gupta   +15 more
semanticscholar   +1 more source

Acute safety, efficacy, and advantages of a novel cryoballoon ablation system for pulmonary vein isolation in patients with paroxysmal atrial fibrillation: initial clinical experience

Europace, 2021
Aims Cryoballoon pulmonary vein isolation (PVI) is a safe and effective treatment for atrial fibrillation (AF). Current limitations include incomplete vein occlusion due to balloon rigidity and inconsistent electrogram recording, which impairs ...
A. Anić, N. Lever, Andrew Martin, T. Brešković, M. Sulkin, E. Duffy, W. Saliba, M. Niebauer, O. Wazni, N. Varma   +9 more
semanticscholar   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source