Results 101 to 110 of about 238,087 (309)

Effects of pirbuterol and sodium nitroprusside on pulmonary haemodynamics in hypoxic cor pulmonale

, 1983
The acute haemodynamic effects of oral pirbuterol (a beta-agonist) were contrasted with those of sodium nitroprusside, a vasodilator, in six patients with hypoxic chronic bronchitis and emphysema.
Wathen, C G, Macnee, William, Flenley, DC, Hannan, W J, Muir, A.L   +4 more
core  

Establishment of a chronic aspiration pneumonia mouse model using oropharyngeal aspiration of food suspension

Animal Models and Experimental Medicine, EarlyView.
Four aspiration methods (UV, IN, IT, and OA) were compared, and OA was identified as the most effective delivery technique. A chronic aspiration pneumonia model was then established through repeated OA of food suspension or gastric contents. Integrated analyses, including micro‐CT, histopathology, cytokine profiling, and RNA sequencing, revealed ...
Qianwen Li, Fansen Lin, Hongzhi Gao, Yun Zhao, Yuqi Liu   +4 more
wiley   +1 more source

Assessment of pulmonary mechanical properties influence on patternsand indices of their ventilation mechanics in various biologicalconditions

Бюллетень сибирской медицины, 2007
Patterns and mechanics of pulmonary ventilation are studied in sharp experiment on living rabbits (n = 15), after their sacrificing (n = 15) and on isolated lungs (n = 7).
A. I. Karzilov, F. F. Tetenev, T. N. Bodrova   +2 more
doaj   +1 more source

Riociguat versus sildenafil on hypoxic pulmonary vasoconstriction and ventilation/perfusion matching [PDF]

, 2018
Introduction Current treatment with vasodilators for pulmonary hypertension associated with respiratory diseases is limited by their inhibitory effect on hypoxic pulmonary vasoconstriction (HPV) and uncoupling effects on ventilation-perfusion (V'/Q ...
Virginia Chamorro, Daniel Morales-Cano, Francisco Perez-Vizcaino, Morales Cano, Daniel, Mondejar-Parreño, Gema, Javier Milara, Esquivel Ruiz, Sergio Antonio, Moreno, Laura, Esquivel-Ruiz, Sergio, Gema Mondejar-Parreño, María Callejo, Moreno Gutiérrez, Laura, Cortijo, Julio, Pérez Vizcaíno, Francisco, Mondejar Parreño, Gema, Sergio Esquivel-Ruiz, Cogolludo, Ángel, Barberá, Joan A, Chamorro, Virginia, Callejo, María, Julio Cortijo, Morales-Cano, Daniel, Ángel Cogolludo, Barreira, Bianca, Barberà i Mir, Joan Albert, Cogolludo Torralba, Ángel Luis, Barberá, Joan A., Milara, Javier, Joan A. Barberá, Callejo Arranz, María, Laura Moreno, Perez-Vizcaino, Francisco, Bianca Barreira   +32 more
core   +1 more source

SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

Animal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang, Xuepei Lei, Yiying Huang, Jiaming Tang, Guiying Shi, Hang Li, Lin Bai   +6 more
wiley   +1 more source

FUNCTIONAL RESPONSE TO ENDOBRONCHIAL VALVE IMPLANTING TO THOSE SUFFERING FROM PULMONARY DESTRUCTIVE TUBERCULOSIS

Туберкулез и болезни лёгких, 2016
Goal of the study: to investigate the changes in ventilation and gas exchange function of the lungs before and after 1-1.5 months after installation of endobronchial valve (EV) aimed at cavity healing in pulmonary destructive tuberculosis patients ...
L. A. Popova, E. A. Shergina, O. V. Lovacheva, T. R. Bagdasaryan, N. A. Chernykh, V. B. Nefedov   +5 more
doaj   +1 more source

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus

Animal Models and Experimental Medicine, EarlyView.
This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li, Ziqing Jia, Zhe Cong, Jianrong Ma, Jiahan Lu, Yongzhi Hou, Fei Wang, Jiasen Yang, Ting Chen, Jingjing Zhang, Dong Zhang, Jing Xue   +11 more
wiley   +1 more source

Reasons for Hospital Admissions in Chronic Hypercapnic COPD Patients on Long-Term Nocturnal Noninvasive Ventilation – A Prospective Observational Study

International Journal of COPD
Simon Koschel,1,2,* Sarah Bettina Stanzel,1,2,* Doreen Kroppen,1,2 Marieke Duiverman,3,4 Maximilian Wollsching-Strobel,1,2 Daniel Majorski,1,2 Melanie Patricia Berger,1,2 Falk Schumacher,2,5 Johannes Fabian Holle,2,6 Wolfram Windisch,1,2 ...
Koschel S, Stanzel SB, Kroppen D, Duiverman M, Wollsching-Strobel M, Majorski D, Berger MP, Schumacher F, Holle JF, Windisch W, Zimmermann M   +10 more
doaj  

Ventilation parameters and pulmonary mechanics.

, 2016
Ventilation parameters and pulmonary mechanics.
Helmut D. Hummler (345924), Giuseppe Buonocore (2160628), Wolfgang Bernhard (2160619), Katharina Banke (2160625), Dimitrios Tsikas (399687), Hans Fuchs (345919), Marla R. Wolfson (2160622), Michael Ebsen (91407)   +7 more
core   +1 more source

Morphometric analysis of postnatal lung development in the gray short‐tailed opossum (Monodelphis domestica): An ultrastructural study

The Anatomical Record, EarlyView.
Abstract An ultrastructural morphometric analysis of the postnatal development of the lung in the gray short‐tailed opossum (Monodelphis domestica) has been conducted to evaluate the morphofunctional status of this poorly developed marsupial lung immediately following parturition.
Kirsten Ferner
wiley   +1 more source