Results 241 to 250 of about 329,849 (308)

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

open access: yesPediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics   +16 more
wiley   +1 more source

A Novel Method for Generating a Fused Ventilation–Perfusion Map Using CT‐Derived Ventilation and FDG‐PET for Lung Functional Avoidance in Radiotherapy: A Feasibility Study

open access: yesPrecision Radiation Oncology, EarlyView.
This study retrospectively analyzed two types of respiratory phase CT and PET/CT images of 20 lung cancer patients. After DIR and functional grading, three lung function images were developed, and their correlations and differences were evaluated. Abstract Background Pulmonary ventilation–perfusion function plays a crucial role in both radiotherapy ...
Suyan Bi   +4 more
wiley   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said   +10 more
wiley   +1 more source

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

open access: yesPhytotherapy Research, EarlyView.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng   +8 more
wiley   +1 more source

Prognostic Value of a Cardiopulmonary Exercise Testing‐Derived Summed Score in Idiopathic Pulmonary Fibrosis and Connective Tissue Disease‐Associated Interstitial Lung Disease: A Prospective Cohort Study

open access: yesRespirology, EarlyView.
A cardiopulmonary exercise testing‐derived summed score effectively predicted mortality or lung transplantation risk in newly diagnosed interstitial lung disease. Higher summed scores (2–5) were associated with markedly lower event‐free survival rates.
Yu‐Lin Tsai   +6 more
wiley   +1 more source

Studies of granulocyte function (chemiluminescence response) in postoperative infection [PDF]

open access: yes, 1987
Inthorn, D.   +6 more
core  

PULMONARY VENTILATION IN PREGNANCY*

BJOG: An International Journal of Obstetrics & Gynaecology, 1978
SummarySerial tests of ventilatory function were made in 38 normal primigravidae during and after pregnancy. During pregnancy all patients showed major changes in tidal volume, functional residual capacity and residual volume. Minor changes were found in many other measurements, all of which occurred at an early stage of pregnancy.
A B, Alaily, K B, Carrol
openaire   +2 more sources

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