HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium [PDF]
Background: While acute lung injury (ALI) contributes significantly to critical illness, it resolves spontaneously in many instances. The majority of patients experiencing ALI require mechanical ventilation.
Bonney, Megan +9 more
core +3 more sources
Review of hypoxaemia in the anaesthetized horse: predisposing factors, consequences and management [PDF]
Objectives: To discuss how hypoxaemia might be harmful and why the horse is particularly predisposed to developing it. To review the strategies that are used to manage hypoxaemia in anaesthetised horses, to describe how successful these strategies are
Auckburally, Adam, Nyman, Görel
core +1 more source
Extracorporeal support for patients with acute respiratory distress syndrome. [PDF]
Extracorporeal membrane oxygen (ECMO) has been used for many years in patients with life-threatening hypoxaemia and/or hypercarbia. While early trials demonstrated that it was associated with poor outcomes and extensive haemorrhage, the technique has ...
Finney, SJ
core +3 more sources
Acquired Whole-lung Mismatched Perfusion Defects on Pulmonary Ventilation/Perfusion Scintigraphy. [PDF]
Bowman AW, Albers BK, Jain MK.
europepmc +3 more sources
Extracorporeal CO2 removal in hypercapnic patients who fail noni nvasive ventialtion and refuse endotracheal intubation. a case series [PDF]
Noninvasive ventilation (NIV) represents the standard of care for patients with exacerbation of chronic obstructive pulmonary disease. However, NIV fails in almost 40% of the most severe forms of acute hypercapnic respiratory failure and patients must ...
Alessandri, F +5 more
core +1 more source
An evaluation of the relative efficacy of an open airway, an oxygen reservoir and continuous positive airway pressure 5 cmH2O on the non-ventilated lung [PDF]
Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsThe aim of this study, during one-lung ventilation, was to evaluate if oxygenation could be improved by use of a simple oxygen reservoir or ...
Benumof J.L. +18 more
core +2 more sources
In silico modeling of oxygen-enhanced MRI of specific ventilation. [PDF]
Specific ventilation imaging (SVI) proposes that using oxygen-enhanced 1H MRI to capture signal change as subjects alternatively breathe room air and 100% O2 provides an estimate of specific ventilation distribution in the lung.
Burrowes, Kelly S +6 more
core +1 more source
Management of Mechanical Ventilation in Decompensated Heart Failure. [PDF]
Mechanical ventilation (MV) is a life-saving intervention for respiratory failure, including decompensated congestive heart failure. MV can reduce ventricular preload and afterload, decrease extra-vascular lung water, and decrease the work of breathing ...
Adams, Jason Y +4 more
core +4 more sources
The Role of rescue therapies in the treatment of severe ARDS [PDF]
ARDS is characterized by a non-cardiogenic pulmonary edema with bilateral chest radiograph opacities and hypoxemia refractory to oxygen therapy. It is a common cause of admission to the ICU due to hypoxemic respiratory failure requiring mechanical ...
Alessandri, F, Pugliese, F, Ranieri, M.
core +1 more source
Inhaled nitric oxide as an adjunct to neonatal resuscitation in premature infants: a pilot, double blind, randomized controlled trial. [PDF]
BackgroundNitric oxide (NO) plays an important role in normal postnatal transition. Our aims were to determine whether adding inhaled NO (iNO) decreases supplemental oxygen exposure in preterm infants requiring positive pressure ventilation (PPV) during ...
Anderson, Michael +10 more
core

