Results 121 to 130 of about 150,674 (346)

Update on pulmonary hypertension complicating chronic obstructive pulmonary disease

International Journal of COPD, 2009
Soma Jyothula, Zeenat SafdarPulmonary-Critical Care Medicine, Baylor College of Medicine, Houston, TX, USAAbstract: Pulmonary hypertension (PH) is the hemodynamic manifestation of various pathological processes that result in elevated pulmonary artery ...
Soma Jyothula, Zeenat Safdar
doaj  

Diastolic Pulmonary Artery to Pulmonary Capillary Wedge Pressure Difference: A Predictor of Outcome After Left Ventricular Assist Device Implantation [PDF]

, 2020
Iréne Lang
openalex   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

SP399A NEW TECHNIQUE FOR ESTABLISHING DRY WEIGHT IN HEMODIALYSIS PATIENTS VIA ESTIMATION OF PULMONARY CAPILLARY WEDGE PRESSURE. A TISSUE DOPPLER IMAGING STUDY [PDF]

, 2016
Gürsel Yıldız, Ender Hür, Kemal Mağden, Ferhan Candan, Mansur Kayataş, Mehmet Birhan Yılmaz   +5 more
openalex   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Predictive Value of Pulmonary Capillary Wedge Pressure for Heart Failure Hospitalization in Heart Failure Patients with Cardiac Resynchronization Therapy [PDF]

, 2014
Atsushi Suzuki, Tsuyoshi Shiga, Kentaro Yoshida, Naoki Serizawa, Ken Kato, Koichiro Ejima, Tsuyoshi Suzuki, Tetsuyuki Manaka, Morio Shoda, Nobuhisa Hagiwara   +9 more
openalex   +1 more source

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

Advanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li, Chenli Si, Xue Wang, Xiaojin Wu, Ying Shang, Shengfang Ge, Yong Wang, Yong Zuo, Zhen Zhang   +8 more
wiley   +1 more source

Pulmonary hypertension in adolescents with sickle cell disease [PDF]

, 2016
Sickle cell disease consists of a group of disorders that have a similar mutation in at least one of the beta-globin chains of hemoglobin. This results in a change of the hemoglobin to sickle shaped cells when in the deoxygenated state.
Akinyemi, Katherine
core   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Brain natriuretic peptide: its relevance to the cardiologist [PDF]

, 1995
Brain natriuretic peptide, or Btype natriuretic peptide (BNP), is a cardiac hormone secreted mainly from the ventricles. It is natriuretic, diuretic, vasodilaton, lowers blood pressure and suppresses the renin-angiotensin-aldosterone system.
Cheung, BMY
core