Results 41 to 50 of about 473,330 (302)

An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue

Advanced Healthcare Materials, EarlyView.
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale, Deborah Stanco, Roberta Visone, Bernd Stadlinger, Pierfrancesco Pagella, Marco Rasponi, Thimios A. Mitsiadis   +6 more
wiley   +1 more source

Stress behaviour across human tooth by temperature gradient resulting of laser irradiation

Journal of Mechanical Engineering and Sciences, 2020
The authors report the simulation of temperature distribution and thermally induced stress in the premolar tooth under ND-YAG pulsed laser beam. The Three-Phase-Lag (TPL) non-Fourier model is proposed to describe the heat conduction in the human tooth ...
S. Falahatkar, A. Nouri-Borujerdi, M. Najafi   +2 more
doaj   +1 more source

Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond

Advanced Science, EarlyView.
Dental stem cell (DSC) aging involves genomic instability, mitochondrial dysfunction, telomere attrition, and epigenetic alterations, leading to impaired proliferation, reduced differentiation potential, and pro‐inflammatory secretory activity. These processes drive cellular senescence and compromise regenerative and immunomodulatory functions, thereby
Xinyuan Zhao, Yunfan Lin, Pei Lin, Ye Lu, Jiarong Zheng, Xu Chen, Zihao Zhou, Li Cui   +7 more
wiley   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Reliability of Radiovisiography and Cytomorphometry in Determining the Age of an Individual: A Clinical Comparative Study

Journal of Pharmacy and Bioallied Sciences
The oral cavity can be explored as an area to identify the impacts of aging. Exfoliative cytology is a painless, rapid, and effective method for collecting intact cells from various epithelial layers for microscopic examination.
Mohanty Satyam, Bhuvaneshwari S, Manohar Balaji, Bhuyan Lipsa, Kaur Awneet   +4 more
doaj   +1 more source

Thermal irritation of teeth during dental treatment procedures

Restorative Dentistry & Endodontics, 2013
While it is reasonably well known that certain dental procedures increase the temperature of the tooth's surface, of greater interest is their potential damaging effect on the pulp and tooth-supporting tissues.
Su-Jung Kwon, Yoon-Jung Park, Sang-Ho Jun, Jin-Soo Ahn, In-Bog Lee, Byeong-Hoon Cho, Ho-Hyun Son, Deog-Gyu Seo   +7 more
doaj   +1 more source

Multiscale Design of Dental Restorative Materials: Mechanistic Foundations, Technological Innovations, and Clinical Translation

Advanced Science, EarlyView.
From conventional ceramics to bioinspired smart composites, this review charts the evolution of dental restorative biomaterials. Integrating materials innovation, advanced manufacturing technologies, and bioinspired strategies, it presents a roadmap for developing functional, clinically translatable restorations that combine durability, adaptability ...
Bailei Li, Ruixue Ai, Xinjiani Chen, Yaning Wang, Chenlei Pan, Suxian Song, Chenjie Yang, Yu Zhou, Zhen Zhang, Xiaojun Liu, Xiaodi Liu, Liping Yao, Quanbao Zhang, Wenxue Gu, Rongqing Zhang   +14 more
wiley   +1 more source

Modeling chronic periodontitis in rats: Persistent alveolar bone loss mediated by periodontal pathogens

Animal Models and Experimental Medicine, EarlyView.
Irrigation of periodontal pockets with human periopathogens, in combination with a 14‐day ligature‐induced periodontitis protocol, significantly enhances alveolar bone loss and sustains bacterial colonization for up to 28 days following ligature removal, thereby more closely replicating the chronic nature of human periodontitis compared to the ligature
Maksym Skrypnyk, Chun Xu, Shlomo Berkovsky, Thilini Jayasinghe, Axel Spahr   +4 more
wiley   +1 more source

Synapsids and sensitivity: Broad survey of tetrapod trigeminal canal morphology supports an evolutionary trend of increasing facial tactile specialization in the mammal lineage

The Anatomical Record, EarlyView.
Abstract The trigeminus nerve (cranial nerve V) is a large and significant conduit of sensory information from the face to the brain, with its three branches extending over the head to innervate a wide variety of integumentary sensory receptors, primarily tactile.
Juri A. Miyamae, Julien Benoit, Irina Ruf, Zoleka Sibiya, Bhart‐Anjan S. Bhullar   +4 more
wiley   +1 more source

Microenvironment Influences Odontogenic Mesenchymal Stem Cells Mediated Dental Pulp Regeneration

Frontiers in Physiology, 2021
Dental pulp as a source of nutrition for the whole tooth is vulnerable to trauma and bacterial invasion, which causes irreversible pulpitis and pulp necrosis. Dental pulp regeneration is a valuable method of restoring the viability of the dental pulp and
Xiaoyao Huang, Xiaoyao Huang, Xiaoyao Huang, Zihan Li, Zihan Li, Zihan Li, Anqi Liu, Anqi Liu, Anqi Liu, Xuemei Liu, Xuemei Liu, Xuemei Liu, Hao Guo, Hao Guo, Hao Guo, Meiling Wu, Meiling Wu, Meiling Wu, Xiaoxue Yang, Xiaoxue Yang, Xiaoxue Yang, Bing Han, Bing Han, Bing Han, Kun Xuan, Kun Xuan, Kun Xuan   +26 more
doaj   +1 more source