Results 21 to 30 of about 7,386 (205)

Identification of key module and hub genes in pulpitis using weighted gene co-expression network analysis

BMC Oral Health, 2023
Background Pulpitis is a common disease mainly caused by bacteria. Conventional approaches of diagnosing the state of dental pulp are mainly based on clinical symptoms, thereby harbor deficiencies.
Denghui Zhang, Chen Zheng, Tianer Zhu, Fan Yang, Yiqun Zhou   +4 more
doaj   +1 more source

Ligand-gated ion channel P2X7 regulates hypoxia-induced factor-1α mediated pain induced by dental pulpitis in the medullary dorsal horn

Frontiers in Molecular Neuroscience, 2022
Dental pulpitis often induces severe pain, and the molecular immune response is remarkable in both peripheral and central nervous system. Accumulating evidence indicates that activated microglia in the medullary dorsal horn (MDH) contribute to dental ...
Jing Zhang, Jialin Si, Rongrong Liang, Rongrong Liang, Yuxin Lu, Hongwei Shang, Xinwei Li, Shukai Sun, Li-an Wu   +8 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

PMAIP1 mediates endoplasmic reticulum stress in human dental pulp stem cells during pulpitis pathogenesis

BMC Oral Health
Background Pulpitis, characterized by dental pulp inflammation, significantly impacts oral health, yet its molecular mechanisms remain poorly understood.
Caixia Zhou, Jiali Zhang, Luyi Chen, Yanheng Yu, Yingying Sun, Yunping Pan, Song Cai, Ping Zhong   +7 more
doaj   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

The P2x4r-Bdnf Pathway In Microglia Mediates Pulpitis-Induced Pain

International Dental Journal
Aim or purpose: The analgesia effect of pulpitis is not satisfaction, we Investigating the central mechanisms of pulpitis pain to provide a basis for analgesic targets in pulpitis.
Xiaojing Li, Yubo Liu, Shukai Sun
doaj   +1 more source

Evaluation of 6‐Month Knowledge Retention and Satisfaction After Pedagogical Escape Games in Dentistry

Journal of Dental Education, EarlyView.
ABSTRACT Purpose To evaluate 6‐month knowledge retention and long‐term satisfaction after two pedagogical escape games (PEGs) addressing foundational (3D printing) and clinical (pediatric dentistry) content in a dental curriculum. Methods In this monocentric serial cross‐sectional study, immediate post‑PEG knowledge was assessed in fifth‑year dental ...
Lina Grich, Elisabeth Dursun, Stephane Le‐Goff, Sarah Abdel‐Gawad, Helene Gouze, Maria‐Antonietta D'Agostino, Jean‐Pierre Attal, Sandrella Hamdan, Philippe Francois   +8 more
wiley   +1 more source

Enhanced exosome secretion regulated by microglial P2X7R in the medullary dorsal horn contributes to pulpitis-induced pain

Cell & Bioscience
Background Pulpitis is a prevalent oral disease characterized by severe pain. The activation of microglia in the medullary dorsal horn (MDH) is reportedly essential for the central sensitization mechanism associated with pulpitis.
Jing Zhang, Zhuo Yu, Mingjun Wang, Xiaoning Kang, Xiaoke Wu, Fengjiao Yang, Lu Yang, Shukai Sun, Li-an Wu   +8 more
doaj   +1 more source

Surface Micro‐Discharge Plasma for Multiple Teeth Bleaching: Efficacy, Mechanism and Safety

High Voltage, EarlyView.
ABSTRACT Hydrogen peroxide (H2O2) is the commonly‐used bleaching chemical in clinical practice, but its excessive concentrations can cause tooth damage. Atmospheric pressure cold plasma is considered a promising new technique for tooth bleaching. Surface micro‐discharge (SMD) devices can generate large‐scale plasma, which holds potential for treating ...
Ruike Chen, Haoran Feng, Yinglong Li, Hong Pan, Hangbo Xu, Zhen Jiao, Dongjie Cui, Ruonan Ma   +7 more
wiley   +1 more source

Mouse Model of Lipopolysaccharide (LPS)-Induced Pulpitis

Bio-Protocol
Pulpitis is an important and prevalent disease within the oral cavity. Thus, animal models are necessary tools for basic research focused on pulpitis. Researchers worldwide often use dogs and miniature pigs to construct animal models of pulpitis. However,
Lanting Shao, Baian Chen, Ying Zheng
doaj   +1 more source