Results 31 to 40 of about 17,449 (249)

N4-Acetylcytidine Of Circxpo6 Triggers Mapk Pathway To Promote Pulpitis

International Dental Journal
Aim or purpose: Although N4-acetylcytidine (ac4C) modification affects the stability of mRNA, and lncRNA, and regulates miRNA production, it is unknown whether it exists in circular non-coding RNAs (circRNA), and the molecular mechanism on circRNA ...
Li Lin
doaj   +1 more source

Ligand-gated ion channel P2X7 regulates hypoxia-induced factor-1α mediated pain induced by dental pulpitis in the medullary dorsal horn

Frontiers in Molecular Neuroscience, 2022
Dental pulpitis often induces severe pain, and the molecular immune response is remarkable in both peripheral and central nervous system. Accumulating evidence indicates that activated microglia in the medullary dorsal horn (MDH) contribute to dental ...
Jing Zhang, Jialin Si, Rongrong Liang, Rongrong Liang, Yuxin Lu, Hongwei Shang, Xinwei Li, Shukai Sun, Li-an Wu   +8 more
doaj   +1 more source

Postoperative Pain After The Use Of A Dexamethasone Rinse As An Irrigant Prior To Obturation [PDF]

, 2013
Purpose: The purpose of this randomized, double-blind pilot study was to determine the effect of dexamethasone on post-operative pain when used as an intracanal rinse prior to obturation.
Tarabishy, Kenan
core   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

PMAIP1 mediates endoplasmic reticulum stress in human dental pulp stem cells during pulpitis pathogenesis

BMC Oral Health
Background Pulpitis, characterized by dental pulp inflammation, significantly impacts oral health, yet its molecular mechanisms remain poorly understood.
Caixia Zhou, Jiali Zhang, Luyi Chen, Yanheng Yu, Yingying Sun, Yunping Pan, Song Cai, Ping Zhong   +7 more
doaj   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

The P2x4r-Bdnf Pathway In Microglia Mediates Pulpitis-Induced Pain

International Dental Journal
Aim or purpose: The analgesia effect of pulpitis is not satisfaction, we Investigating the central mechanisms of pulpitis pain to provide a basis for analgesic targets in pulpitis.
Xiaojing Li, Yubo Liu, Shukai Sun
doaj   +1 more source

Dental Pathology in Selected Carnivores from Arkansas [PDF]

, 1989
The occurrence and kinds of dental pathology in wild carnivore populations in Arkansas were investigated through examination of 1295 skulls of bobcat (Felis rufus), river otter (Lutra canadensis), gray fox (Urocyon cinereoargenteus), coyote (Canis ...
McDaniel, V. Rick, Tumlison, C. Renn, Wilhide, J. D.   +2 more
core   +2 more sources

Generative Artificial Intelligence–Driven Clinical Case Simulation in Temporomandibular Disorder Education: ChatGPT Versus Real Patients

Journal of Dental Education, EarlyView.
ABSTRACT Background Temporomandibular disorders (TMDs) and orofacial pain (OFP) demand advanced diagnostic and clinical reasoning skills in dental education. Traditional simulations with real patients face limitations in availability and standardization.
Paula Rodrigues‐Pereira, Maria Amália Pereira Dias‐Calças, Alex Moreira Mélo, Melissa de Oliveira Melchior, Lucas Gaspar Ribeiro, Antônio Pazin‐Filho, Jardel Francisco Mazzi‐Chaves, Laís Valencise Magri   +7 more
wiley   +1 more source

Enhanced exosome secretion regulated by microglial P2X7R in the medullary dorsal horn contributes to pulpitis-induced pain

Cell & Bioscience
Background Pulpitis is a prevalent oral disease characterized by severe pain. The activation of microglia in the medullary dorsal horn (MDH) is reportedly essential for the central sensitization mechanism associated with pulpitis.
Jing Zhang, Zhuo Yu, Mingjun Wang, Xiaoning Kang, Xiaoke Wu, Fengjiao Yang, Lu Yang, Shukai Sun, Li-an Wu   +8 more
doaj   +1 more source