Results 31 to 40 of about 6,954 (202)

Enhanced exosome secretion regulated by microglial P2X7R in the medullary dorsal horn contributes to pulpitis-induced pain

Cell & Bioscience
Background Pulpitis is a prevalent oral disease characterized by severe pain. The activation of microglia in the medullary dorsal horn (MDH) is reportedly essential for the central sensitization mechanism associated with pulpitis.
Jing Zhang, Zhuo Yu, Mingjun Wang, Xiaoning Kang, Xiaoke Wu, Fengjiao Yang, Lu Yang, Shukai Sun, Li-an Wu   +8 more
doaj   +1 more source

Mouse Model of Lipopolysaccharide (LPS)-Induced Pulpitis

Bio-Protocol
Pulpitis is an important and prevalent disease within the oral cavity. Thus, animal models are necessary tools for basic research focused on pulpitis. Researchers worldwide often use dogs and miniature pigs to construct animal models of pulpitis. However,
Lanting Shao, Baian Chen, Ying Zheng
doaj   +1 more source

Pulp Therapies Rooted in Evidence: IAPD Porto Declaration. [PDF]

Int J Paediatr Dent
International Journal of Paediatric Dentistry, Volume 36, Issue 2, Page 387-390, March 2026.
Dhar V, El-Karim I, Coll JA, Fouad AF, O'Connell AC, Asgary S, Bjørndal L, Cehreli ZC, Crystal YO, Ekambaram M, Hodgson BD, Innes NP, Rodrigues JA, Taha NA, Tewari N, Turk T.   +15 more
europepmc   +2 more sources

In Vitro Evaluation of Novel Calcium Silicate‐Based and Resin‐Modified Calcium Silicate Materials: Cytocompatibility and Mineralization Potential on Human Dental Pulp Stem Cells for Pulp Repair

Microscopy Research and Technique, EarlyView.
This study demonstrates that Biodentine XP exhibits superior cytocompatibility, promotes odontogenic differentiation, and enhances mineralization in human dental pulp stem cells, supporting its use in regenerative endodontics. Resin‐modified materials showed lower bioactivity, highlighting the importance of material composition in pulp therapy outcomes.
Francisco Javier Rodríguez‐Lozano, Nuria Pérez‐Guzmán, Paula García‐Rios, David García‐Bernal, Adrián Lozano, Sergio López‐García   +5 more
wiley   +1 more source

Comparative efficacy of novel bioactive glass versus sodium fluoride toothpaste for dentin hypersensitivity

Journal of Periodontology, EarlyView.
Abstract Background This first‐in‐human clinical study aimed to evaluate the safety and efficacy of a bioglass incorporated in a toothpaste, in reducing dentin hypersensitivity (DH) compared to a sodium fluoride (NaF) toothpaste over a 2‐week period. Methods A double‐blind, randomized, parallel‐arm, proof‐of‐concept clinical trial was conducted with 46
Hatice Hasturk, Daniel Boyd, Kathleen MacDonald‐Parsons, Stephanie Turner‐Cahill, Joon Seong, Nicola West, Heather J. Doucette   +6 more
wiley   +1 more source

The Effect of Myrmecodia pendans Ethanol Extract on Inflamed Pulp: Study on Sprague Dawley Rats

MCBS (Molecular and Cellular Biomedical Sciences), 2019
Background: Inflammation is a body response caused by injury and infection. Pulpitis is a pulp tissue inflammation which is the continuous process of pulp hyperemia by bacteria invasion.
Janti Sudiono, Meylisa Hardina
doaj   +1 more source

Evaluation of Postoperative Pain Frequency in Single-Session Endodontic Treatments With Patency and Foraminal Enlargement. [PDF]

Clin Exp Dent Res
ABSTRACT Objective This study aimed to evaluate the incidence of postoperative pain in single‐session endodontic treatments with foraminal instrumentation, considering factors such as pulpal diagnosis, tooth position, type of endodontic sealer, and sealer extrusion.
Godoy VB, Limoeiro AG, Sandini V, Mehta V, Nascimento WM, Marceliano-Alves MFV, Frozoni M.   +6 more
europepmc   +2 more sources

Oral Health‐Related Quality of Life of Western Australian Refugee Children With Childhood Caries

Australian Dental Journal, EarlyView.
ABSTRACT Objectives Dental caries remains the most common chronic childhood condition and in Australia persists as a leading cause of potentially preventable hospitalisation. Despite various public health initiatives and improvements in oral health among the wider community, significant disparities exist among refugee families due to the unique ...
Jilen Patel, Joshua Tze Jen Ong, Sarah Cherian, Zac Dempsey, Bathsheba Turton, Robert Anthonappa   +5 more
wiley   +1 more source

Diagnostic utility of Th2 cytokines (IL-4, IL-5, IL-10, and IL-13) in pulpal blood for assessing pulpitis severity

BMC Oral Health
Objective To evaluate the diagnostic utility of T-helper type 2 (Th2) cytokines, specifically Interleukin-4 (IL-4), IL-5, IL-10, and IL-13, in distinguishing different stages of pulpitis and their combined performance in clinical diagnosis.
Qun Li
doaj   +1 more source

Thymosin Α1 Inhibiting Ferroptosis Of Dental Pulp Cells In Pulpitis

International Dental Journal
Aim or purpose: This study aimed to uncover the role of ferroptosis in pulpitis and assess whether thymosin α1 could alleviate pulpitis by inhibiting ferroptosis in dental pulp cells.
Jie Wu, Gong Qimei, Tong Zhongchun, Liao Zekai, Liu Wenxuan   +4 more
doaj   +1 more source