Results 71 to 80 of about 7,386 (205)

Dentine Regeneration With Calcium Strontium Silicate: In Vitro Odontogenic Differentiation, Antimicrobial Activity, Immunomodulation and In Vivo Pulpotomy in Rat Molars

open access: yesInternational Endodontic Journal, Volume 59, Issue 9, Page 1871-1886, September 2026.
ABSTRACT Aim This study examined the in vitro and in vivo performance of calcium strontium silicate (CSR) as a novel biomaterial for vital pulp therapy (VPT), assessing its odontogenic differentiation, antibacterial activity, immunomodulation, inflammatory response and dentine regeneration potential compared to calcium silicate (CS) and Mineral ...
Mohamed Mahmoud Abdalla   +4 more
wiley   +1 more source

Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk

open access: yesInternational Endodontic Journal, Volume 59, Issue 9, Page 1743-1759, September 2026.
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar   +4 more
wiley   +1 more source

Vital Pulp Therapy Of Mature Permanent Teeth With Irreversible Pulpitis

open access: yesInternational Dental Journal
Introduction: In this case, full pulpotomy was performed on a mature permanent tooth with irretrievable pulpitis. After 2 years’ follow-up, the result was satisfactory, indicating that VPT can be a prospective option for irretrievable pulpitis in mature ...
Xiaoru Zhu, Wenxi He
doaj   +1 more source

Clinical and Psychosocial Predisposing Factors Associated With Anaesthesia Failure During Non‐Surgical Root Canal Treatment: A National Dental Practice‐Based Research Network Study

open access: yesInternational Endodontic Journal, Volume 59, Issue 9, Page 1817-1830, September 2026.
ABSTRACT Aim This study aimed to identify dentist, patient, and pre‐treatment clinical characteristics associated with local anaesthesia failure during non‐surgical endodontic treatment. Methodology Data were collected from the National Dental Practice‐Based Research Network study entitled “Predicting Outcomes of Root Canal Treatment (PREDICT)”, which ...
Linda J. Liu   +9 more
wiley   +1 more source

Identifying Potential Biomarkers Of Pulp Inflammation In Dentinal Fluid

open access: yesInternational Dental Journal
Aim or purpose: To identify potential biomarkers in dentinal fluid in teeth with reversible and irreversible pulpitis using mass spectrometry-based proteomics technology. Materials and methods: Dentinal fluid samples were collected from fifty vital third
Diana Ostanina   +4 more
doaj   +1 more source

The Survival and Success of Teeth With External Cervical Resorption: A Multi‐Centre, Retrospective Study

open access: yesInternational Endodontic Journal, Volume 59, Issue 9, Page 1841-1857, September 2026.
ABSTRACT Objectives To evaluate the survival and success outcomes of teeth affected by external cervical resorption (ECR) managed using three distinct treatment strategies, with periapical radiographs and small field of view cone beam computed tomography used for diagnosis and treatment planning.
Shanon Patel   +6 more
wiley   +1 more source

Differential Regulation of Angiogenesis, Lymphangiogenesis, and Neural Tissue in Normal and Inflamed Dental Pulp: Immunohistochemical Analysis

open access: yesDiagnostics
Background/Objectives: Pulp inflammation impairs healing, yet the underlying vascular and neural mechanisms remain poorly understood. This study investigated the differential regulation of lymphatic vessels, blood vessels, and neural tissue in pulpitis ...
Nooruldeen Ammar Alani   +1 more
doaj   +1 more source

Regenerative Endodontics in Teeth With Irreversible Pulpitis: A Scoping Review

open access: yesInternational Endodontic Journal, Volume 59, Issue 9, Page 1792-1803, September 2026.
ABSTRACT Introduction Regenerative endodontic procedures (REPs) have been widely used to manage a range of pulpal pathologies, particularly in immature permanent teeth. The development of bioactive calcium silicate–based materials has led to a paradigm shift in vital pulp therapy (VPT) and REPs.
Mahmoud Torabinejad   +2 more
wiley   +1 more source

ATF3 triggers M2 macrophage polarization to protect against pulp inflammation through WNT4 regulation

open access: yesActa Biochimica et Biophysica Sinica
Pulpitis is a common inflammatory oral disease that can lead to pulp necrosis. The aim of this study is to investigate the expression and regulatory mechanisms of ATF3, a potential therapeutic marker, in pulpitis.
Liu Liu   +4 more
doaj   +1 more source

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