Results 1 to 10 of about 354 (138)

Performance Enhancement in Hafnium Oxide Through Homogeneous and Heterogeneous co‐Doping Strategies

Advanced Electronic Materials, EarlyView.
This article presents a comprehensive co‐doping toolkit to optimize the performance and reliability of fluorite‐structure ferroelectrics like hafnium oxide. By employing homogeneous and heterogeneous co‐doping strategies, precise control over crystallization behavior, polarization hysteresis, and oxygen vacancy distribution is achieved.
Shouzhuo Yang, David Lehninger, Markus Neuber, Amir Pourjafar, Yannick Raffel, Ayse Sünbül, Anant Rastogi, Peter Reinig, Thomas Kämpfe, Konrad Seidel, Maximilian Lederer   +10 more
wiley   +1 more source

A comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster

Animal Models and Experimental Medicine, EarlyView.
This study presents the first comprehensive proteome and phosphoproteome atlas of the Chinese hamster across nine organs (heart, liver, lung, kidney, spleen, cerebral cortex, skeletal muscle, stomach, and testis or ovary). A total of 14 219 proteins were identified in the proteome, with 11 828 phosphorylated proteins and 47 122 phosphorylation sites ...
Luyao Zhang, Tao Ding, Wanjun Peng, Jie Kong, Xiaoyue Tang, Jiyu Xu, Qiaochu Wang, Zhiyi Zhang, Chunmei Shi, Yizhuo Tian, Huilan Yang, Yehong Yang, Yue Wu, Xiaoyan Liu, Jiangfeng Liu, Juntao Yang   +15 more
wiley   +1 more source

Proteomics‐Based Identification of the Pyroptosis‐Related Biomarker PCSK9 and Its Association With the Pathogenesis of Rheumatoid Arthritis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang, Hao‐Jie Chen, Ting‐Ting Wu, Xin‐Yi Shen, Ying‐Ying Gao, Yu‐Feng Yin, Tian Ren, Xin Chu, Jing Cao, Tao Cheng, Ming‐Jun Wang   +10 more
wiley   +1 more source

A Perspective of Multi‐Reflecting TOF MS

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Time‐of‐flight mass spectrometry (TOF MS) excels in rapid and high‐sensitivity analysis, making it a cornerstone of analytical chemistry. But as sample complexity explodes in omics studies, so does the need for higher resolving power to ensure accurate results.
A. N. Verenchikov, V. V. Makarov, A. V. Vorobyev, S. N. Kirillov   +3 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Distinct Proteomic Signatures Driving Progression of Sarcopenia: A Longitudinal Multicohort Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Sarcopenia is an age‐related condition characterized by progressive muscle mass, strength and physical performance declines, contributing to frailty and adverse health outcomes. Despite increasing interest in molecular biomarkers, longitudinal data with external validation are limited.
Sung Hye Kong, Ok Hee Jeon, Ji Yeon Kim, Miji Kim, Jinhee Kim, Seung Shin Park, Hak Chul Chang, Chang Won Won, Dohyun Han   +8 more
wiley   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang, Heng Yang, Xinjie Gao, Zengyu Zhang, Ruiyuan Weng, Yuchao Fei, Jiabin Su, Hanqiang Jiang, Wei Ni, Yuxiang Gu   +9 more
wiley   +1 more source

Multifunctional Carbon‐Nanotube Supported Catalyst for Efficient Glycerol Hydrogenolysis to 1,2‐propanediol

ChemCatChem, Volume 18, Issue 5, 13 March 2026.
ABSTRACT Multiwall carbon nanotube (NC7000) supported mono‐, bi‐, and trimetallic catalysts were synthesized and tested in a multi‐batch reactor setup supported by data‐driven modeling for the chemical hydrogenolysis of glycerol to 1,2‐Propanediol (1,2‐PDO) at 220°C under 30 bar hydrogen pressure in aqueous solution. ICP‐OES, N2‐physisorption, scanning
Dominique Lumpp, Samrin Shaikh, Fabian Riebesehl, Charlotte Ruhmlieb, Kai Kruber, Baldur Schroeter, Irina Smirnova, Mirko Skiborowski, Bodo Fiedler, Jakob Albert   +9 more
wiley   +1 more source

JWST/NIRSpec Reveals the Atmospheric Driver of Saturn's Variable Magnetospheric Rotation Rate

Journal of Geophysical Research: Space Physics, Volume 131, Issue 3, March 2026.
Abstract Past measurements of Saturn's upper atmosphere have allowed only a broad scale view of the temperature and ion density structures within the auroral region. However, Saturn's auroral currents include a planetary period current component that is produced by neutral atmospheric flows.
Tom S. Stallard, Luke Moore, Henrik Melin, Chris G. A. Smith, Omakshi Agiwal, M. Nahid Chowdhury, Rosie E. Johnson, Katie L. Knowles, Emma M. Thomas, Paola I. Tiranti, James O’Donoghue, Khalid Mohamed, Ingo Mueller‐Wodarg, John C. Coxon, Sarah V. Badman, Joe A. Caggiano   +15 more
wiley   +1 more source

Optimizing the predictive validity of NIRS kinetic profiles to predict aerobic capacity from a resting skeletal muscle occlusion test

Experimental Physiology, Volume 111, Issue 3, Page 738-750, 1 March 2026.
Abstract Measuring and monitoring individual cardiorespiratory fitness through a valid and accessible non‐exhaustive surrogate is required. Techniques measuring haemodynamics have shown promise, and this study aimed to optimize the predictive validity of these approaches alongside developing predictive equations.
Heru Syarli Lesmana, Kyohei Marume, Justin S. Lawley   +2 more
wiley   +1 more source