Results 101 to 110 of about 5,179,678 (338)

Impact of competitive flow on wall shear stress in coronary surgery: computational fluid dynamics of a LIMA-LAD model [PDF]

open access: yes, 2010
Competitive flow from native coronary vessels is considered a major factor in the failure of coronary bypass grafts. However, the pathophysiological effects are not fully understood.
Haverstaad, Rune   +8 more
core   +2 more sources

Wireless blood pressure sensor implantation in sheep: A detailed technique

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Twelve adult sheep underwent wireless blood pressure sensor implantation. The procedure lasted an average of 36 min, with mean systolic and diastolic blood pressures of 93 ± 6 and 65 ± 5 mmHg, respectively. This rapid, minimally invasive protocol is a powerful platform for cardiovascular device development.
David Santer   +10 more
wiley   +1 more source

Computer simulation of platelet activation in a pulsatile ventricular assist device, through finite elements and a simplified geometry [PDF]

open access: yes, 2017
Ventricular assist devices are a technological solution for patients who suffer from cardiac insufficiency and await a transplant. In this work, a new design of an implantable pulsatile blood pump is analyzed in terms of blood damage, by means of finite ...
Berli, Marcelo Eduardo   +4 more
core  

Prediction of Turbulent Shear Stresses through Dysfunctional Bileaflet Mechanical Heart Valves using Computational Fluid Dynamics

open access: yes, 2018
There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease.
Gamage, Peshala T.   +2 more
core   +1 more source

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma   +2 more
wiley   +1 more source

Study of pulsatile pressure-driven electroosmotic flows through an elliptic cylindrical microchannel with the Navier slip condition

open access: yesAdvances in Difference Equations, 2017
This paper aims to study an unsteady electric field-driven and pulsatile pressure-driven flow of a Newtonian fluid in an elliptic cylindrical microchannel with Navier boundary wall slip.
Pearanat Chuchard   +2 more
doaj   +1 more source

Spatial model of convective solute transport in brain extracellular space does not support a "glymphatic" mechanism. [PDF]

open access: yes, 2016
A "glymphatic system," which involves convective fluid transport from para-arterial to paravenous cerebrospinal fluid through brain extracellular space (ECS), has been proposed to account for solute clearance in brain, and aquaporin-4 water channels in ...
Jin, Byung-Ju   +2 more
core  

Non-Newtonian Rheology in Blood Circulation

open access: yes, 2014
Blood is a complex suspension that demonstrates several non-Newtonian rheological characteristics such as deformation-rate dependency, viscoelasticity and yield stress.
Sochi, Taha
core   +2 more sources

Porcine kidney xenotransplantation: From primate models to clinical reality

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo   +3 more
wiley   +1 more source

An Experimental Study of Pulsatile Flow in a Compliant Aortic Root Model under Varied Cardiac Outputs

open access: yesFluids, 2018
The fluid dynamics of a natural aortic valve are complicated due to the highly pulsatile flow conditions, the compliant wall boundaries, and the sophisticated geometry of the aortic root.
Ruihang Zhang, Yan Zhang
doaj   +1 more source

Home - About - Disclaimer - Privacy