Results 121 to 130 of about 43,390 (300)

Posture-dependent cerebrospinal fluid flow measurement in the optic nerve subarachnoid space using multi-delay 2D interslice saturation MRI

Brain Research Bulletin
Recent studies have indicated that CSF dynamics within the optic nerve subarachnoid space (ONSAS) may play an important role in the progression of optic diseases.
Minjae Kim, Sung-Hong Park
doaj   +1 more source

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Vascular implications of non-pulsatile flow extracorporeal life support

Journal of Cardiothoracic Surgery
Extracorporeal life support has become a widely integrated tool in treating refractor cardiopulmonary failure. Under normal physiologic conditions, arterial blood flow is inherently pulsatile, and cyclic shear stress plays a pivotal role in maintaining ...
Alex Bartlett, Antonio Gachineiro
doaj   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Transcranial Color‐Coded Duplex Sonography in Large‐Vessel Vasculitis Compatible With Takayasu Arteritis Presenting Intracranial Involvement and Vertebrobasilar Dolichoectasia: A Case Report

Journal of Clinical Ultrasound, EarlyView.
This case illustrates sequential intracranial occlusions in large‐vessel vasculitis compatible with Takayasu arteritis preserving perfusion through robust collateral pathways. Transcranial color‐coded duplex sonography identified characteristic blunted flow patterns and focal turbulence, underscoring its value in detecting hemodynamic compromise beyond
Maria Júnia Lira e Silva, Jordana Gaudie Gurian, Isabella Mesquita Venâncio, Eva Carolina Rocha, Gisele Sampaio Silva   +4 more
wiley   +1 more source

Sonographic Diagnosis of an Intercostal Artery Pseudoaneurysm: A Case Report and Literature Review

Journal of Clinical Ultrasound, EarlyView.
A 63‐year‐old male presented to the emergency department after being found unconscious during a welfare check. Following a prolonged three‐month hospital admission, the patient developed left flank pain. Spectral Doppler ultrasound revealed a large isoechoic lesion with layering echoes, and spectral Doppler demonstrated bidirectional flow.
Aaditya P. Singh, Peter R. Coombs
wiley   +1 more source

On-Chip AC Electrothermal Pump for Pulsatile Perfusion

Micromachines
Microphysiological systems (MPSs) have emerged as promising platforms for drug discovery and in vitro pharmacological testing. MPSs aid to reproduce physiologically relevant microenvironments, in which controlled perfusion can play important role.
Itaru Kawata, Sosuke Kobayashi, Yoshiyasu Ichikawa, Masahiro Motosuke   +3 more
doaj   +1 more source

The transitional regime of pulsatile pipe flow [PDF]

The presence of turbulence in the circulatory system is thought to lead to cardiovascular diseases. Despite its importance, turbulence transition in cardiovascular flows is not well understood.
Morón Montesdeoca, Daniel
core   +1 more source

Liquid Crystal Elastomers Filaments for Adaptive Textiles and Soft Robotics: A Processing‐Centric Review

Macromolecular Rapid Communications, EarlyView.
Liquid crystal elastomer (LCE) filaments are fabricated through extrusion with in‐process UV curing, enabling controlled flow alignment and network locking of mesogens. The resulting structure responds to thermal or optical stimuli, inducing molecular reorientation and macroscopic contraction.
Anne Schwarz‐Pfeiffer, Shazia Mehtab
wiley   +1 more source