Results 71 to 80 of about 5,179,678 (338)

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

open access: yesAdvanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies   +14 more
wiley   +1 more source

Pulsatile flow analysis in a bend square channel by modal decomposition

open access: yesEPJ Web of Conferences, 2014
The article analyzes the results of numerical simulations of pulsatile flow in a square channel with a 90° bend using Proper Orthogonal Decomposition (POD).
Manoch Lukáš   +3 more
doaj   +1 more source

Combinations of Hydrostatic Pressure and Shear Stress Time-dependently Decrease E-selectin, VCAM-1 and ICAM-1 Expression Induced by Tumor Necrosis Factor-Alpha in Cultured Endothelial Cells

open access: yesJournal of Biomechanical Science and Engineering, 2012
Endothelial cells (ECs) are constantly subjected to shear stress, a tangential stress generated by blood flow, and hydrostatic pressure, a normal stress generated by blood pressure.
Hiromichi NAKADATE   +3 more
doaj   +1 more source

Control system for an artificial heart [PDF]

open access: yes, 1970
Inexpensive industrial pneumatic components are combined to produce control system to drive sac-type heart-assistance blood pump with controlled pulsatile pressure that makes pump rate of flow sensitive to venous /atrial/ pressure, while stroke is ...
Gebben, V. D., Webb, J. A., Jr.
core   +1 more source

Pulsatile ocular blood flow [PDF]

open access: yesBritish Journal of Ophthalmology, 1998
Although the eye is the only organ in the body in which blood vessels are readily visible, a technique for the accurate and reproducible measurement of ocular blood flow and its component parts has proved elusive.1 The increasing likelihood of a multifactorial pathogenesis for glaucoma and possible importance of optic nerve head perfusion in the ...
openaire   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

open access: yesAdvanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng   +15 more
wiley   +1 more source

Preliminary Implementation of the Next Generation Cannulation Simulator [PDF]

open access: yes, 2019
© 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new ...
Abdallah, Omrane   +11 more
core   +2 more sources

A Dynamic 3D Human Liver Sinusoid Model for Mechanistic Interrogation of Fontan‐Associated Liver Disease

open access: yesAdvanced Science, EarlyView.
This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab   +14 more
wiley   +1 more source

Pulsatile Flow Patterns in Distensible Tubes [PDF]

open access: yesCirculation Research, 1966
Pulsatile flow patterns in polyvinyl tubes were visualized by means of streaming birefringence and compared with those obtained using an electromagnetic flowmeter. At low flow rates the frequency spectrum of the birefringence pattern is similar to that of volume flow.
E O, Attinger   +3 more
openaire   +2 more sources

Silicon‐Embedded Multifunctional Heterogeneous Integration for Miniaturized Photoplethysmography Detection Devices

open access: yesAdvanced Science, EarlyView.
ABSTRACT The multifunctional integration of chips with high flexibility and scalable manufacturing is crucial for enhancing chip performance, reducing chip size, and simplifying chip design. However, balancing volume, cost, flexibility, and functionality using traditional heterogeneous integration methods is challenging.
Lang Chen   +7 more
wiley   +1 more source

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