Results 71 to 80 of about 43,390 (300)

Aortic wave dynamics and its influence on left ventricular workload. [PDF]

PLoS ONE, 2011
The pumping mechanism of the heart is pulsatile, so the heart generates pulsatile flow that enters into the compliant aorta in the form of pressure and flow waves.
Niema M Pahlevan, Morteza Gharib
doaj   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

Advanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin, Mark Epshtein, Yahel Talmon, Tirosh Mekler, Itay Or, Mahli Raad, Gil Bolotin, Josué Sznitman, Netanel Korin   +8 more
wiley   +1 more source

Pulsatile flow blood pump [PDF]

, 2017
The invention is about a next-generation blood pump that provides pulsatile blood flow, and has been developed for cardiopulmonary by-pass devices used for maintaining extracorporeal blood circulation during heart surgeries and the supportive devices of ...
Oran, Elif
core   +2 more sources

Estimation of pulsatile energy dissipation in intersecting pipe junctions using inflow pulsatility indices

AIP Advances, 2021
This study aims to characterize the effect of inflow pulsatility on the hydrodynamic power loss inside intersecting double-inlet, double-outlet pipe intersection (DIPI) with cross-flow mixing.
Reza Rasooli, Onur Dur, Kerem Pekkan
doaj   +1 more source

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

Advanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo, Jinglei Wang, Xin Wang, Han Feng, Yize Zhao, Fadong Li, Shaobin Wei, Le Zhou, Zixu Zhao, Songjie Chen, Xiangyi Kong, Jue Wang, Liu He, Shijun Xia, Xin Li, Junmeng Zhang, Xiaoxia Liu, Xueyuan Guo, Ning Zhou, Songnan Li, Chenxi Jiang, Ribo Tang, Caihua Sang, Deyong Long, Xin Du, Jianzeng Dong, Wenwu Zhu, Changsheng Ma   +27 more
wiley   +1 more source

Combinations of Hydrostatic Pressure and Shear Stress Time-dependently Decrease E-selectin, VCAM-1 and ICAM-1 Expression Induced by Tumor Necrosis Factor-Alpha in Cultured Endothelial Cells

Journal of Biomechanical Science and Engineering, 2012
Endothelial cells (ECs) are constantly subjected to shear stress, a tangential stress generated by blood flow, and hydrostatic pressure, a normal stress generated by blood pressure.
Hiromichi NAKADATE, Eiichi SEKIZUKA, Shigeru AOMURA, Haruyuki MINAMITANI   +3 more
doaj   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

Numerical data of nonlinear optimal perturbation growth in pulsatile pipe flow [PDF]

Pulsatile fluid flows through straight pipes undergo a sudden transition to turbulence that is extremely difficult to predict. The difficulty stems here from the linear Floquet stability of the laminar flow up to large Reynolds numbers, well above ...
Keuchel, Patrick, Avila, Marc
core   +1 more source

Simulation and experimental comparison between pulsatile and steady flow. [PDF]

, 2013
(A) Simulation results of FGF-2 in the outflow as a function of time for pulsatile (○) or steady (•) flow, (B) Simulation results of FGF-2 bound along the endothelial-lined hollow fiber as a function of distance at 44 sec (pulsatile (○), steady (pink ...
Kimberly Forsten-Williams (360291), Jun Zhang (48506), Bing Zhao (29538), Changjiang Zhang (360290), Michael Fannon (360292)   +4 more
core   +1 more source