Results 71 to 80 of about 36,168 (295)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

The RR Lyrae Luminosity Metallicity Relation Revisited

open access: yesThe Astronomical Journal
We utilize a set of internally consistent absolute ages for a sample of ten Galactic globular clusters to determine the variation of the slope with the zero point of the M _V (RR) ∼ [Fe/H] relation for RR Lyrae variables.
Ata Sarajedini
doaj   +1 more source

Taking Advantage of the COS Time-Tag Capability: Observations of Pulsating Hot DQ White Dwarfs and Discovery of a New One

open access: yes, 2011
We present an analysis of the ultraviolet light curves of five Hot DQ white dwarfs recently observed with the Cosmic Origins Spectrograph (COS) on board the Hubble Space Telescope (HST).
Bergeron, P.   +4 more
core   +1 more source

Gaia Data Release 2: Variable stars in the colour-absolute magnitude diagram [PDF]

open access: yes, 2018
The ESA Gaia mission provides a unique time-domain survey for more than 1.6 billion sources with G ~ 21 mag. We showcase stellar variability across the Galactic colour-absolute magnitude diagram (CaMD), focusing on pulsating, eruptive, and cataclysmic ...
L. Eyer   +134 more
semanticscholar   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Follow-up observations of pulsating subdwarf B stars: Multisite campaigns on PG 1618+563B and PG 0048+091

open access: yes, 2007
We present follow-up observations of pulsating subdwarf B (sdB) stars as part of our efforts to resolve the pulsation spectra for use in asteroseismological analyses.
A.‐Y. Zhou   +22 more
core   +1 more source

Nationwide Survey of Atopic Myelitis and Plexin D1‐Immunoglobulin G‐Related Pain

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To elucidate the features of plexin D1‐immunoglobulin (Ig)G‐associated neuropathic pain and its relationship to atopic myelitis (AM) in a nationwide Japanese survey. Methods A preliminary survey questionnaire was sent to 1574 selected departments (neurology and pediatrics/pediatric neurology) to explore the numbers of AM and plexin ...
Jun‐ichi Kira   +10 more
wiley   +1 more source

A Study of Two Newly-Discovered Eclipsing Binary Systems [PDF]

open access: yes, 2013
I have observed three newly-discovered variable stars using the 16-inch telescope and CCD at the Valparaiso University Observatory. Of these three variables, two have been verified as binary star systems, where one of the stars passes in front of the ...
Bain, Austin
core   +1 more source

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