Results 31 to 40 of about 5,310 (260)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Bounding of earthquake response via critical double impulse for efficient optimal design of viscous dampers for elastic‐plastic moment frames

Japan Architectural Review, 2022
An input velocity adjustment method of the critical double impulse (DI) is presented for efficient design of viscous dampers for elastic‐plastic moment frames.
Hiroki Akehashi, Izuru Takewaki
doaj   +1 more source

Fuzzy-Valued Intensity Measures for Near-Fault Pulse-Like Ground Motions

Computer-Aided Civil and Infrastructure Engineering, 2013
Two fuzzy-valued (FV) structure-specific intensity measures (IMs), one based on squared spectral velocity and the other on inelastic spectral displacement, are presented to characterize near-fault pulse-like ground motions for performance-based seismic design and assessment of concrete frame structures.
Hao Li, Wei-Jian Yi, Xian-Xun Yuan
openaire   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

A practical framework for performance-based reliability analysis of subway stations based on a fault–structure combined system

Journal of Rock Mechanics and Geotechnical Engineering, 2023
It is necessary to pay particular attention to the uncertainties that exist in an engineering problem to reduce the risk of seismic damage of infrastructures against natural hazards.
M. Ghorbanzadeh, M. Hajihassani, M. Kharghani   +2 more
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Comparison between the Effects of Near- and Far-Fault Ground Motions on the Seismic Response of a Soil-Pile-Structure System [PDF]

Journal of Structural and Construction Engineering, 2016
Ground motions recorded in near-fault sites, where the rupture propagates toward the site, are significantly different from those observed in far-fault regions.
Saeed Abbasi Karafshani, Alireza Ardakani Ardakani, Mansoor Yakhchalian   +2 more
doaj  

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source

Extrusion‐Based Additive Manufacturing of Advanced Ceramics: Strengthening Mechanisms and Process Optimization Review

Advanced Engineering Materials, EarlyView.
This review comprehensively evaluates extrusion‐based additive manufacturing for advanced ceramics, detailing feedstock options and key process parameters. By critically addressing defect mechanisms like porosity and cracking, the work highlights optimization strategies through machine learning and advanced postprocessing.
Meisam Bakhtiari, Mohammad Hadi Sheikh‐Ansari, Avinash Borgaonkar, Mehran Dadkhah, Abdollah Saboori   +4 more
wiley   +1 more source