Results 21 to 30 of about 814,794 (268)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman +10 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A new pulse generator for pulsed ESR
Measurement Science and Technology, 1990 The construction of a new high-resolution multichannel low-cost pulse generator is reported. It is fully computer controlled through a simple RS232 serial interface. Its features are 1 ns resolution within any time, pulse delays up to 16 ms and pulse lengths up to 65 mu s, and pulse sequence repetition rate from 66 Hz up to 250 kHz.
Lovy, Dominique, Pluss, J.B., Bill, Hans
openaire +3 more sources
Electrical engineering & Electromechanics, 2018 Purpose. A high-voltage underwater electric explosion, realized by discharging a capacitor into a water gap, is characterized by three main stages: the stage of formation of the plasma channel, the channel stage and post-discharge one. Substantially, the
V. G. Zhekul +4 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
What Do We Hear When We Hear Microbe Sounds
Pulse, 2022 The concept of the Anthropocene, based on the premise that mankind has become a major geological force in its own right, has grown into a central theme with issues such as ecological crisis, climate change, or sustainable futures.
Emre Sünter
doaj +1 more source
Arteriosclerosis and atherosclerosis assessment in clinical practice: Methods and significance
Pulse, 2023 Alongside cancer, cardiovascular disease (CVD) exhibits the highest rates of morbidity and mortality globally, in western society as well as in Asian countries.
Jeong Bae Park, Alberto Avolio
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The Soundscape of Man in the Holocene: An Exercise in Sensitization
Pulse, 2022 This paper discusses how the natural soundscape of Max Frisch’s novella Man in the Holocene (1979) affords a contemplation on the inadequacy of human epistemology against the immense temporality of the geological deep time.
Dong Xia
doaj +1 more source