Results 31 to 40 of about 814,794 (268)
FEBS Letters, EarlyView.The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
USE OF EXPLOSION ENERGY FOR STRENGTHENING WORKING BODIES OF SOIL- CULTIVATING MACHINES [PDF]
Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2013 The research has defined technological methods that combine energy use of explosives and traditional methods of surface treatment (quenching and tempering) to improve the parameters of agricultural machinery.
V.V. Semashko +2 more
doaj
From Proving Ground to Bumblehive: Touring Utah’s Weird Information Landscape [PDF]
Pulse, 2021 The American state of Utah has emerged as an important infrastructural and experimental hub for large-scale information science and communication technology endeavors: both Meta (formerly Facebook) and the US intelligence community maintain massive data ...
Owen Marshall
doaj
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Elektrotehnìka ta Elektroenergetika, 2015 Обрано критеріальні параметри, що дозволяють достовірно оцінювати термостабільність експлуатаційних властивостей діелектричних рідин. Проаналізовано зміну експлуатаційних властивостей трансформаторного масла Т-1500 в ході його взаємодії з пропіленовою і ...
A. P. Malyushevska +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Chirped-pulse amplification with narrowband pulses
Optics Letters, 2010 We demonstrate a compact hyperdispersion stretcher and compressor pair that permit chirped-pulse amplification in Nd:YAG. We generate 750 mJ, 0.2 nm FWHM, 10 Hz pulses recompressed to an 8 ps near-transform-limited duration. The dispersion-matched pulse compressor and stretcher impart a chirp of 7300 ps/nm, in a 3 m x 1 m footprint.
M Y, Shverdin +8 more
openaire +3 more sources
Stringlike Pulse Quantification Study by Pulse Wave in 3D Pulse Mapping [PDF]
The Journal of Alternative and Complementary Medicine, 2012 A stringlike pulse is highly related to hypertension, and many classification approaches have been proposed in which the differentiation pulse wave (dPW) can effectively classify the stringlike pulse indicating hypertension. Unfortunately, the dPW method cannot distinguish the spring stringlike pulse from the stringlike pulse so labeled by physicians ...
Ching-Hsing, Luo +6 more
openaire +2 more sources