Results 51 to 60 of about 1,185,745 (318)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Experimental investigation of the impact of optical injection on vital parameters of a gain-switched pulse source [PDF]
, 2007 An analysis of optical injection on a gain-switched distributed feedback (DFB) laser and its impact on pulse parameters that influence the performance of the pulse source in high-speed optical communication systems is presented in this paper.
Besnard, Pascal +10 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
USE OF EXPLOSION ENERGY FOR STRENGTHENING WORKING BODIES OF SOIL- CULTIVATING MACHINES [PDF]
Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2013 The research has defined technological methods that combine energy use of explosives and traditional methods of surface treatment (quenching and tempering) to improve the parameters of agricultural machinery.
V.V. Semashko +2 more
doaj
Elektrotehnìka ta Elektroenergetika, 2015 Обрано критеріальні параметри, що дозволяють достовірно оцінювати термостабільність експлуатаційних властивостей діелектричних рідин. Проаналізовано зміну експлуатаційних властивостей трансформаторного масла Т-1500 в ході його взаємодії з пропіленовою і ...
A. P. Malyushevska +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Few-cycle fiber pulse compression and evolution of negative resonant radiation
, 2014 We present experimental observations of the spectral expansion of fs-pulses compressing in optical fibers. Using the input pulse frequency chirp we are able to scan through the pulse compression spectra and observe in detail the emergence of negative ...
McLenaghan, J. +1 more
core +1 more source
Spectral characterisation of nk pulse position modulation format [PDF]
, 2005 nk pulse position modulation (PPM) is a new modulation format that has recently been proposed for the optical wireless channel. This Letter considers, for the first time, a full spectral characterisation of -PPM and presents original expressions, which
Cryan, R.A., Menon, M.
core +1 more source
Spectral meta-moments reveal hidden signatures of vortex pulses [PDF]
EPJ Web of Conferences, 2019 Ultrashort vortex pulses possess specific spatio-spectral signatures due to Gouy phase shift. Helical movement of anomalies around the phase singularity was found which is referred to as spectral Gouy rotation. The analysis of spectral moments allows for
Liebmann Max +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source