Results 51 to 60 of about 2,302,476 (295)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Nature CommunicationsMechanistic insights into photodissociation dynamics of transition metal carbonyls, like Fe(CO)5, are fundamental for understanding active catalytic intermediates.
Aviad Schori +25 more
doaj +1 more source
Elektrotehnìka ta Elektroenergetika, 2015 Обрано критеріальні параметри, що дозволяють достовірно оцінювати термостабільність експлуатаційних властивостей діелектричних рідин. Проаналізовано зміну експлуатаційних властивостей трансформаторного масла Т-1500 в ході його взаємодії з пропіленовою і ...
A. P. Malyushevska +2 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
USE OF EXPLOSION ENERGY FOR STRENGTHENING WORKING BODIES OF SOIL- CULTIVATING MACHINES [PDF]
Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2013 The research has defined technological methods that combine energy use of explosives and traditional methods of surface treatment (quenching and tempering) to improve the parameters of agricultural machinery.
V.V. Semashko +2 more
doaj
High-harmonic generation from artificially stacked 2D crystals
Nanophotonics, 2023 We report a coherent layer-by-layer build-up of high-order harmonic generation (HHG) in artificially stacked transition metal dichalcogenides (TMDC) crystals in their various stacking configurations.
Heide Christian +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Elektrotehnìka ta Elektroenergetika, 2019 Purpose. Assessment of the current state, design features and development prospects of electric-discharge submersible devices for well treatment. Methodology. Analysis of the principle of operation and design of electric-discharge submersible devices for
O.V. Khvoshchan +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source