Results 61 to 70 of about 4,099,910 (388)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Single photon generation by pulsed excitation of a single dipole [PDF]

open access: yes, 2000
The fluorescence of a single dipole excited by an intense light pulse can lead to the generation of another light pulse containing a single photon.
A. Dräbenstedt   +27 more
core   +4 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

CURRENT STATE AND PERSPECTIVES OF DEVELOPMENT OF DESIGN OF ELECTRIC DISCHARGE SUBMERSIBLE DEVICES FOR TREATMENT OF WELLS

open access: yesElektrotehnìka ta Elektroenergetika, 2019
Purpose. Assessment of the current state, design features and development prospects of electric-discharge submersible devices for well treatment. Methodology. Analysis of the principle of operation and design of electric-discharge submersible devices for
O.V. Khvoshchan   +2 more
doaj   +1 more source

High-harmonic generation from artificially stacked 2D crystals

open access: yesNanophotonics, 2023
We report a coherent layer-by-layer build-up of high-order harmonic generation (HHG) in artificially stacked transition metal dichalcogenides (TMDC) crystals in their various stacking configurations.
Heide Christian   +6 more
doaj   +1 more source

Correction of Arbitrary Errors in Population Inversion of Quantum Systems by Universal Composite Pulses

open access: yes, 2014
We introduce universal broadband composite pulse sequences for robust high-fidelity population inversion in two-state quantum systems, which compensate deviations in any experimental parameter (e.g.
Genov, Genko T.   +3 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

USE OF EXPLOSION ENERGY FOR STRENGTHENING WORKING BODIES OF SOIL- CULTIVATING MACHINES [PDF]

open access: yesФизико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2013
The research has defined technological methods that combine energy use of explosives and traditional methods of surface treatment (quenching and tempering) to improve the parameters of agricultural machinery.
V.V. Semashko   +2 more
doaj  

Using electric fields for pulse compression and group velocity control

open access: yes, 2016
In this article, we experimentally demonstrate a new way of controlling the group velocity of an optical pulse by using a combination of spectral hole burning, slow light effect and linear Stark effect in a rare-earth-ion-doped crystal.
Kinos, Adam   +4 more
core   +1 more source

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