Results 41 to 50 of about 460,467 (309)

Cyclic resistance change in perpendicularly magnetized Co/Ni nanowire induced by alternating current pulse injection

open access: yes, 2016
We report on cyclic anisotropic magnetoresistance change induced by current pulse injection in perpendicularly magnetized Co/Ni nanowire. By alternating the polarity of the injection pulse, domain walls (DWs) can be deterministically created and ...
Tan, Funan   +5 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Dual-pulse laser induced breakdown spectroscopy in the vacuum ultraviolet with ambient gas: spectroscopic analysis and optimization of limit of detection of carbon and sulfur in steel [PDF]

open access: yes, 2012
Laser Induced Breakdown Spectroscopy (LIBS) in the vacuum ultraviolet (VUV) spectral region was applied to standard steel samples in dual-pulse excitation mode with an ambient gas. Two lasers were employed in collinear geometry, one as an ablation laser (
Jiang, Xi
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The study of Zn–Co alloy coatings electrochemically deposited by pulse current [PDF]

open access: yesHemijska Industrija, 2012
The electrochemical deposition by pulse current of Zn-Co alloy coatings on steel was examined, with the aim to find out whether pulse plating could produce alloys that could offer a better corrosion protection. The influence of on-time and the average
Tomić Milorad V.   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Electrodepositing Pt by modulated pulse current on a nafion-bonded carbon substrate as an electrode for PEMFC

open access: yes, 2007
Polymer electrolyte membrane fuel cell (PEMFC) electrodes were platinized by modulated pulse current electrodeposition. The aim of this study is to look for a way that keeps the advantages but circumvents the disadvantages of electrodeposting Pt for ...
Wei, Z. D.   +6 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Effect of Pulse Current-Assisted Rolling on the Interface Bonding Strength and Microstructure of Cu/Al Laminated Composite

open access: yesMetals, 2020
In this paper, Cu/Al laminated composite was prepared by adopting the pulse current-assisted rolling method, and the microstructure and mechanical properties of the material were investigated.
Hao Song   +5 more
doaj   +1 more source

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