Results 211 to 220 of about 12,580 (254)

Pulsed field ablation for atrial fibrillation

Expert Review of Medical Devices
Atrial fibrillation is the most common sustained arrhythmia, associated with substantial morbidity and a reduced quality of life. The current standard of care, transcatheter pulmonary vein isolation using thermal ablation techniques, provides symptom relief but carries a risk of collateral tissue damage.
Vedran Pašara, Tommaso Sattin, Carlo De Asmundis, Gian-Battista Chierchia, Gezim Bala   +4 more
openaire   +3 more sources

Pulsed Field Ablation in Ventricular Arrhythmias

Cardiac Electrophysiology Clinics
Pulsed field ablation (PFA) is a novel nonthermal energy source for catheter ablation, which is potentially useful also for ablation of ventricular arrhythmias since it mitigates the risk of collateral damage to adjacent tissues and may better penetrate through the scar tissue.
Josef, Kautzner, Petr, Peichl
openaire   +2 more sources

Pulsed field catheter ablation in atrial fibrillation

Trends in Cardiovascular Medicine, 2022
Catheter ablation (CA) has become the mainstay therapy for the maintenance of sinus rhythm in patients with atrial fibrillation (AF), with pulmonary vein isolation (PVI) the most frequently used treatment strategy. Although several energy sources have been tested (including radiofrequency, cryothermal and laser), these are not devoid of safety issues ...
Luigi Di Biase, Juan Carlos Diaz, Xiao-Dong Zhang, Jorge Romero   +3 more
openaire   +2 more sources

The VARIPULSE Pulsed Field Ablation Platform

Cardiac Electrophysiology Clinics
The VARIPULSE platform including a variable loop catheter, TRUPULSE Generator, and CARTO 3 Mapping System VARIPULSE Service Pack Software, has been developed to deliver pulsed field ablation (PFA) in combination with the benefits of electroanatomical mapping. In preclinical studies, delivery of PFA using the VARIPULSE platform has been found to be safe
Reshma, Amin, Mattias, Duytschaever
openaire   +2 more sources

Tissue Selectivity of Pulsed Field Ablation

Cardiac Electrophysiology Clinics
Over the last 2 decades, thermal-based catheter ablation has remained the mainstay treatment of cardiac arrhythmias. Although rare, thermal ablation can extend beyond the myocardium resulting in serious adverse events namely pulmonary vein stenosis, esophagus and phrenic nerve injury.
Chadi, Tabaja, Mohamad, Mdaihly, Charbel, Noujaim, Oussama M, Wazni, Pasquale, Santangeli   +4 more
openaire   +2 more sources

[Pulsed field ablation : The ablation technique of the future?]

Herzschrittmachertherapie & Elektrophysiologie, 2022
The ablation of cardiac arrhythmias is now standard therapy in invasive electrophysiology with a focus on atrial fibrillation due to its high prevalence. Thermal energy sources such as radiofrequency or cryoablation are the most commonly used techniques to date.
Nico, Reinsch, Anna, Füting, Dennis, Höwel, Kars, Neven   +3 more
openaire   +1 more source

Biophysics of Electroporation and Pulsed Field Ablation

Cardiac Electrophysiology Clinics
High-voltage electric fields can lead to increased permeability of cell membranes-a phenomenon called electropermeabilization. The mechanisms contributing to this effect are electroporation, membrane lipid peroxidation, oxidative stress, and structural changes in membrane proteins.
Moritz, Nies, Jacob S, Koruth
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Lesion Characteristics of Pulsed Field Ablation

Cardiac Electrophysiology Clinics
Pulsed field ablation (PFA) has emerged as a promising, nonthermal technique for arrhythmia ablation, leveraging high-voltage electrical fields to induce electroporation and create precise ablation lesions. Unlike traditional thermal methods such as radiofrequency ablation (RFA) and cryoablation, PFA selectively targets myocardial cells while sparing ...
Charbel, Noujaim, Chadi, Tabaja, Oussama M, Wazni, Pasquale, Santangeli   +3 more
openaire   +2 more sources

„Pulsed field ablation“

Herzschrittmachertherapie + Elektrophysiologie, 2022
Nico Reinsch, Anna Füting, Dennis Höwel, Kars Neven   +3 more
openaire   +1 more source

Catheters and Tools with Pulsed Field Ablation—Pulmonary Vein Isolation and Nanosecond Pulse Field Ablation

Cardiac Electrophysiology Clinics
Pulse field ablation (PFA) has gained attention in the field of atrial fibrillation catheter treatment recently. All currently used or developed technologies use ultrashort pulses (on the order of microseconds). The Emerging CellFX System (Pulse Biosciences, Inc, Inc) utilizes nanosecond PFA (nsPFA) and is thus several orders of magnitude shorter than ...
Jan, Petru, Moritoshi, Funasako, Petr, Neuzil   +2 more
openaire   +2 more sources