Results 91 to 100 of about 1,388,804 (348)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Nonlinear Compression of Besselon Waves for High Repetition-Rate Subpicosecond Pulse Trains [PDF]

, 2020
Anastasiia Sheveleva, Christophe Finot
openalex   +1 more source

PSR B0826-34: Sometimes a rotating radio transient

, 2012
We report on the detection of sporadic, strong single pulses co-existing with a periodic weak emission in the duration of weak mode of PSR B0826-34. The intensities and durations of these pulses are comparable with that of the sub-pulses in the strong ...
Abdurixit, D., Esamdin, A., Manchester, R. N., Niu, H. B.   +3 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

A study of strong pulses detected from PSR B0656+14 using Urumqi 25-m radio telescope at 1540MHz

, 2012
We report on the properties of strong pulses from PSR B0656+14 by analyzing the data obtained using Urumqi 25-m radio telescope at 1540 MHz from August 2007 to September 2010.
Ali Esamdin, Cairns, Cordes, Guo-Cun Tao, Hankins, Hui-Dong Hu, Jing Li, Johnston, Joshi, Knight, Knight, Lorimer, Manchester, Mao-Fei Qian, Na Wang, Ritchings, Romani, Weisberg, Weltevrede, Wolszczan   +19 more
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Temporal properties of gamma-ray bursts as signatures of jets from the central engine

, 2001
A comprehensive temporal analysis has been performed on the 319 brightest GRBs with T90>2s from the BATSE current catalog. The rise times, fall times, full-widths at half maximum (FWHM), pulse amplitudes and pulse areas were measured and the frequency ...
Arneodo, Atteia, B. McBreen, Band, Belli, Beloborodov, Berger, Bhat, Borgonovo, Brainerd, Castro-Tirado, Chang, Cordes, Costa, Crider, D. Watson, Daigne, Dermer, Eichler, F. Quilligan, Fenimore, Frail, Fryer, Golenetskii, Gögüs, Hanlon, Hurley, Hurley, Hurley, Ioka, K. J. Hurley, Kluzniak, Kobayashi, Kouveliotou, L. Hanlon, Lee, Lee, Li, Liang, Link, MacFadyen, Mallat, Mallat, Mallozzi, Mazets, McBreen, McBreen, Montroll, Mészáros, Mészáros, Mészáros, Nemiroff, Norris, Norris, Paciesas, Paczynski, Paczynski, Panaitescu, Pendleton, Piran, Preece, Quilligan, Ramirez-Ruiz, Ramirez-Ruiz, Rees, Rees, Rhoads, Ruffert, S. McBreen, Salmonson, Sari, Schaefer, Schmidt, Spada, Stern, Stern, Strohmayer, Thompson, Usov, van Paradijs, van Putten, Young   +81 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Genetic variations for post emergence herbicide tolerance in field pea (Pisum sativum)

The Indian Journal of Agricultural Sciences, 2019
Weeds are highly competitive to the crops for nutrient and water from soil, sunlight, space and also harbour many insect-pest and diseases, consequently lead to drastic yield reduction.
A K PARIHAR, N KUMAR, C P NATH, A K SINGH, S K CHATURVEDI, G P DIXIT, N P SINGH   +6 more
doaj   +1 more source