Results 101 to 110 of about 27,668 (261)

Pembrolizumab for Early‐Stage Triple‐Negative Breast Cancer: KEYNOTE‐522 Japan Subgroup Analysis

Cancer Science, EarlyView.
In the global, phase 3 KEYNOTE‐522 study of high‐risk early‐stage triple‐negative breast cancer (TNBC), neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab improved efficacy outcomes versus neoadjuvant chemotherapy alone. In this analysis of Japanese participants from KEYNOTE‐522, neoadjuvant pembrolizumab plus chemotherapy ...
Masato Takahashi, Hirofumi Mukai, Toshimi Takano, Koichiro Tsugawa, Kenichi Inoue, Mitsuya Itoh, Junichiro Watanabe, Yuko Tanabe, Naohito Yamamoto, Yasuo Miyoshi, Kenichi Watanabe, Toru Mukohara, Yibin Kong, Masashi Shimura, Francisco Beca, Peter Schmid, Hiroji Iwata   +16 more
wiley   +1 more source

KRAB Zinc‐Finger Protein ZNF205 Promotes Hepatocellular Carcinoma via p53 Pathway Repression

Cancer Science, EarlyView.
ZNF205 functions as a critical oncogenic regulator in hepatocellular carcinoma (HCC), where it interacts with p53 and functionally suppresses its transcriptional activity by competitively inhibiting p53 binding to target gene promoters. This p53 inactivation mechanism critically contributes to tumor progression in HCC. ABSTRACT The tumor suppressor p53
Xiaofen Huang, Yingchuan Yang, Yuan Ma, Wei Hao, Jingzhuo Jin, Yue Ding, Yiming Zhang, Xiuyuan Zhang, Xinli Li, Qin Song, Jiaqi Liu, Bingxin Liu, Yuanjun Zhai, Chunling Zhao, Jin Wu, Chunyan Tian   +15 more
wiley   +1 more source

Use of species’ responses to cryptic anthropogenic disturbances for monitoring biodiversity outcomes in tropical forests

Conservation Biology, EarlyView.
Abstract Measuring area‐based conservation outcomes in tropical forests is challenging due to cryptic human disturbances (e.g., hunting). As a result, comparative studies of management strategies providing quantitative outcomes remain scarce, especially in the Neotropics.
Lucy Perera‐Romero, Roan McNab, Rony Garcia‐Anleu, John Polisar, Chris Sutherland, Daniel Thornton   +5 more
wiley   +1 more source

Puma concolor

, 1993
Published as part of W. Christopher Wozencraft, 1993, Order Carnivora, pp. 279-348 in Mammal Species of the World (2 nd Edition), Washington and London :Smithsonian Institution Press on pages 296-297, DOI: 10.5281/zenodo ...
openaire   +1 more source

Automating the analysis of public saliency and attitudes toward biodiversity from digital media

Conservation Biology, EarlyView.
Abstract Measuring public attitudes toward wildlife provides crucial insights into human relationships with nature and helps monitor progress toward Global Biodiversity Framework targets. Yet, conducting such assessments at a global scale presents challenges.
Noah Giebink, Amrita Gupta, Diogo Veríssimo, Charlotte H. Chang, Tony Chang, Angela Brennan, Brett G. Dickson, Alex Bowmer, Jonathan Baillie   +8 more
wiley   +1 more source

Genetic and Ecological Management of Pacific Salmon Fisheries for the 21st Century

Fisheries Management and Ecology, EarlyView.
ABSTRACT Based on ecological adaptation theory, tremendous effort is being spent on measures that are eliminating salmon hatcheries and fishing opportunities with the intention of protecting wild runs deemed to be of particular genetic importance to the survival of the species.
Randall E. Brummett, Ian G. Cowx, Devin M. Bartley   +2 more
wiley   +1 more source

Making sense of TILs: recommendations for morphological assessment of tumour‐infiltrating lymphocytes in gastro‐oesophageal carcinoma

Histopathology, EarlyView.
This review examines the role of tumour‐infiltrating lymphocytes (TILs) in gastro‐oesophageal carcinoma (GEC), focusing on their composition, clinical relevance and therapeutic utility. It proposes a framework for standardised evaluation and reporting of TILs, addressing GEC‐specific pathology challenges to support the widespread use and validation of ...
Ylva A Weeda, Roberto Salgado, Filip van Herpe, Daniel Sur, Michael Vieth, Sherene Loi, Ahmad P Tafti, Hardas Alexandros, Akira I Hida, Amarpreet Bhalla, Andrey I Khramtsov, Anna Ehinger, Atsushi Tanaka, Balazs Acs, Caner Ercan, Cornelia M Focke, Daniel Ehinger, Dan Huang, Galina F Khramtsova, Haruto Nishida, Nianyi Li, Nickolas Littlefield, Sanna Steen, Selim Sevim, Shin Ichihara, Shinnosuke Morikawa, Stefan Michiels, Thomas Papathomas, Toshihiro Haga, Qiangqiang Gu, Weiqi Sheng, Hoel Kervadec, Hugo M Horlings, Francisco Sanchez‐Vega, Yelena Y Janjigian, Myriam Chalabi, Hanneke W M van Laarhoven, Liudmila L Kodach, Sybren L Meijer   +38 more
wiley   +1 more source

Corporate social (ir)responsibility and firm risk: The role of corporate governance

Journal of Financial Research, EarlyView.
Abstract We study how corporate governance moderates the relationship between corporate social responsibility (CSR), corporate social irresponsibility (CSI), and firm risk. We find that CSR reduces risk for firms with strong governance. In contrast, CSI increases firm risk more significantly for firms with stronger governance, suggesting that backlash ...
Craig Dunbar, Zhichuan Frank Li, Yaqi Shi   +2 more
wiley   +1 more source

¿Se correlacionan los ataques de jaguares Panthera onca y pumas Puma concolor (Carnivora: Felidae) al ganado con la riqueza de especies y la abundancia relativa de presas silvestres?

Revista de Biología Tropical, 2014
Los ataques de grandes felinos al ganado son una de las principales causas de conflicto entre humanos y felinos, siendo por ello un tema prioritario para la conservación de estas especies.
Albert Burgas, Ronit Amit, Bernat C Lopez   +2 more
doaj  

Limited contribution by non‐volant small mammals to regeneration in ironstone rocky outcrops

Restoration Ecology, EarlyView.
Abstract Introduction Animal‐mediated seed dispersal contributes substantially to natural regeneration in degraded areas. However, the role of seed dispersal by non‐volant small mammals (NVSM), mainly marsupials and rodents, in contributing to regeneration remains underexplored, especially in mountaintop, open‐canopy ecosystems.
Maria Fernanda Regiolli Godoi, Vitor Emídio de Mendonça, Adriano Pereira Paglia, Fernando A. O. Silveira   +3 more
wiley   +1 more source