Results 121 to 130 of about 27,668 (261)

The multifaceted role of PUMA in cell death pathways: its therapeutic potential across cancer types. [PDF]

Cell Commun Signal
Tat SS, Mandal K, Sharma T, Ghate NB, Barik GK, Gachhe RN, Santra MK.   +6 more
europepmc   +1 more source

Free rein: Are feral horses competing with native ungulates in British Columbia?

The Journal of Wildlife Management, Volume 90, Issue 3, April 2026.
We investigated little‐studied feral horses in west‐central British Columbia, Canada, as a potential competitor for native moose and mule deer. We did not find strong evidence that feral horses exclude moose or deer from habitat or resources at a large landscape scale or smaller spatiotemporal patch scale.
Katie Tjaden‐McClement, Tazarve Gharajehdaghipour, Carolyn Shores, Shane White, Robin Steenweg, Mathieu Bourbonnais, Zoe Konanz, A. Cole Burton   +7 more
wiley   +1 more source

PUMA-p53 Dysregulation and Ki-67 Overexpression Define Unfavorable Prognostic Signatures in Colorectal Cancer. [PDF]

Cancers (Basel)
Mekras A, Tsavdaris D, Mekras D, Vasilakou A, Paramythiotis D, Michalopoulos A, Bobos M.   +6 more
europepmc   +1 more source

Integrated transcriptomic analysis and experimental validation identify ACADL as a mitochondrial tumor suppressor via the FOXO3a/PUMA axis in lung adenocarcinoma. [PDF]

Eur J Med Res
Wang Y, Ding Y.
europepmc   +1 more source

Design and Application of a Genome‐Wide SNP Array to Improve Conservation Outcomes in the Critically Endangered Southern Corroboree Frog

Molecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT Species‐specific genomic information has the potential to transform modern conservation management strategies through improved genomic assessment and management outcomes. Gaining genomic insights into genetic diversity, adaptability and potential resilience against infectious diseases is essential to enhance conservation efforts for threatened
Mikaeylah J. Davidson, Kyall R. Zenger, J. Scott Keogh, Lee Berger, Lee F. Skerratt, Tiffany A. Kosch   +5 more
wiley   +1 more source

Unraveling the miR-144-3p/PUMA pathway: a novel regulator of FDX1-mediated cuproptosis in colorectal cancer. [PDF]

Cell Oncol (Dordr)
Jia G, Li J, Jiang M, Liu N, Ding N, Jiang X, Zhang G, Tan X, Kang Y, Zhang L, Wang F, Zhang Y.   +11 more
europepmc   +1 more source

A phase 1 study of berzosertib (M6620, VX‐970) in combination with cisplatin and radiation in patients with locally advanced head and neck squamous cell carcinoma (ETCTN 9950)

Cancer, Volume 132, Issue 6, 15 March 2026.
ABSTRACT Background Ataxia telangiectasia Rad3‐related (ATR) protein kinase regulates DNA damage response and is essential for tumor cell survival. Preclinically, ATR inhibition can sensitize tumor cells to radiation and chemotherapy. The authors conducted a phase 1 trial of berzosertib, a selective ATR inhibitor, in combination with definitive ...
Aarti Bhatia, Zhengjia Chen, Yuji Zhang, Justine Yang Bruce, Susanne Arnold, Varinder Kaur, Jonathan W. Riess, Moon Fenton, Barbara Burtness, Nabil F. Saba, Harold Tara, Conor E. Steuer, Dong M. Shin, Garrett Wasp, Thomas H. Davis, Malini Patel, John C. Schmitz, Priyanka Bhateja, Virginia Diavolitsis, Dan P. Zandberg, Darrion L. Mitchell, Brian F. Kiesel, Charles Kunos, Steven D. Gore, Michael Carducci, Jan H. Beumer, Taofeek K. Owonikoko   +26 more
wiley   +1 more source

¿Puma estás?

, 2014
Fil: Castillo, Diego Fabian. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Sur. Departamento de Biologia, Bioquimica y Farmacia.
Luengos Vidal, Estela Maris, Guerisoli, Maria de Las Mercedes, Castillo, Diego Fabian, Caruso, Nicolás   +3 more
openaire   +1 more source

Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling—The CATCH experience

International Journal of Cancer, Volume 158, Issue 6, Page 1675-1689, 15 March 2026.
What's new? CATCH is a prospective precision oncology registry trial that harnesses whole‐genome/exome‐ and RNA‐sequencing to enable actionable biomarker detection in metastatic breast cancer patients of any subtype. The data of the first 412 consecutive patients with completed follow‐up in this real‐world, single‐center patient cohort provide robust ...
Mario Hlevnjak, Sabine Heublein, Verena Thewes, Lukas Wagener, Constantin Pixberg, Carlo Fremd, Laura Michel, Christian Maurer, Lars Buschhorn, Nicola Dikow, Fangyoumin Feng, Stefan Fröhling, Christel Herold‐Mende, Steffen Hirsch, Chen Hong, Daniel Hübschmann, Lena Jassowicz, Polina Kozyulina, Katrin Pfütze, Richard F. Schlenk, Hans‐Peter Sinn, Katharina Smetanay, Christoph Springfeld, Albrecht Stenzinger, Celina Wagner, Stephan Wolf, Andreas Trumpp, Dirk Jäger, Oliver Zivanovic, Marc Zapatka, Andreas Schneeweiss, Peter Lichter   +31 more
wiley   +1 more source

Meningeal lymphatic vessel dysfunction exacerbates brain injury in CVST mice via endoplasmic reticulum and oxidative stress pathways. [PDF]

Front Immunol
Ying J, Li J, Wu X, Chen X, Zhang H, Wei L, Jing J, Wang S.   +7 more
europepmc   +1 more source