Results 91 to 100 of about 129,066 (229)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Fluence and wavelength dependent ultrafast differential transmission dynamics in graphene

Materials Research Express, 2020
We performed degenerate pump-probe transmission measurements of graphene supported on glass for a range of pump fluences that enable us to observe both positive and negative deferential transmission dynamics. Our results show that at an intermediate pump
Rustam Gatamov, Andrey Baydin, Halina Krzyzanowska, Norman Tolk   +3 more
doaj   +1 more source

Coherent generation of symmetry-forbidden phonons by light-induced electron-phonon interactions in magnetite

, 2017
Symmetry breaking across phase transitions often causes changes in selection rules and emergence of optical modes which can be detected via spectroscopic techniques or generated coherently in pump-probe experiments.
Arrell, Christopher, Baldini, Edoardo, Borroni, Simone, Carbone, Fabrizio, Katukuri, Vamshi M., Kozlowski, Andrzej, Legut, Dominik, Lorenzana, José, Mann, Andreas, Oleś, Andrzej M., Parlinski, Krzysztof, Piekarz, Przemyslaw, Teyssier, Jérémie, van Mourik, Frank, Yazyev, Oleg V.   +14 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Extraction of many-body configurations from nonlinear absorption in semiconductor quantum wells

, 2009
Detailed electronic many-body configurations are extracted from quantitatively measured timeresolved nonlinear absorption spectra of resonantly excited GaAs quantum wells.
Cundiff, S. T., Funk, A. C., Kira, M., Koch, S. W., Mirin, R. P., Schafer, M., Smith, R. P., Steiner, J. T., Wahlstrand, J. K.   +8 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Research Paper: Transient Absorption Spectroscopy of Deionized Water by Ti: sapphire Femtosecond Laser Pulses [PDF]

فیزیک کاربردی ایران
Transient absorption spectroscopy allows the observation of excited state dynamics following optical excitation across a wide range of time scales, from femtoseconds to milliseconds.
Fereshteh Hajiesmaeilbaigi, Hosein Razzaghi, Eftekhar Sadat Bostandoost, Asama Sadat Motamedi   +3 more
doaj   +1 more source

Influence of laser-excited electron distributions on the x-ray magnetic circular dichroism spectra: Implications for femtosecond demagnetization in Ni

, 2009
In pump-probe experiments an intensive laser pulse creates non-equilibrium excited electron distributions in the first few hundred femtoseconds after the pulse.
Blaha P., D. Legut, Gómez-Abal R., K. Carva, Koopmans B., Oppeneer P. M., P. M. Oppeneer   +6 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Tunneling Control of Transmission Coefficient and Group Index in a Quantum Dot Nanostructure

Advances in Condensed Matter Physics, 2014
We theoretically study the transmission and group index properties of the probe field in a four-level quantum dot molecule. It is found that the tunnel coupling plays a very important role in realizing the transmission coefficient of the probe field ...
Hamid Reza Hamedi, A. Khaledi-Nasab, H. Ghaforyan   +2 more
doaj   +1 more source