Results 91 to 100 of about 1,697,755 (307)
HEAT PUMP AND AIR CONDITIONING GRADING SYSTEMS AND METHODS [PDF]
An expectation module determines an expected average power consumption of a heat pump for a predetermined period as a function of indoor and outdoor temperatures of the building during the predetermined period.
Alsaleem, Fadi Mohammad
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Investigating the role that the Southern Ocean biological pump plays in determining global ocean oxygen concentrations and deoxygenation [PDF]
Global ocean circulation connects marine biogeochemical cycles through the long-range transport of nutrients and oxygen with the Southern Ocean (SO) acting as a water mass crossroads. The biological pump in the SO has been shown to play an important role
Keller, David, Oschlies, Andreas
core
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Mathematical model of heat pump [PDF]
In this paper different energy states of a heat pump are described. Equations used for mathematical description of the heat pump in the Matlab Simulink are presented.
Pitron, J.
core
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Dependence of quantum correlations of twin beams on pump finesse of optical parametric oscillator
The dependence of quantum correlation of twin beams on the pump finesse of an optical parametric oscillator is studied with a semi-classical analysis.
Changde Xie +9 more
core +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source

