Results 71 to 80 of about 278,773 (245)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Journal of Engineering, 2019 This work consists in assessing a real islanded power system from a dynamic security point of view, to support the planned installation, in the near future, of a hydro power plant with pumped storage, aiming to increase the integration of renewable ...
Maria Helena Vasconcelos +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The Non-intrusive Detection of Incipient Cavitation in Centrifugal Pumps [PDF]
This thesis investigates methods for the detection of incipient cavitation in centrifugal pumps. The thesis begins by describing the working of the centrifugal pump which makes this type of pump particularly prone to cavitation.
Al Thobiani, Faisal
core +2 more sources
On the Design and Response of Domestic Ground-Source Heat Pumps in the UK [PDF]
, 2014 The design and response of ground source heat pumps coupled to vertical closed loop arrays in UK domestic applications are investigated in this article.
Underwood, Chris, Chris Underwood
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Energies, 2019 Researches have over the past few years have been applying optimization algorithms to quickly find optimum parameter combinations during cavitation optimization design.
Ji Pei +5 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Numerical characterization of silicon DC electro-osmotic pumps: the role of the micro channel geometry [PDF]
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Morini, GL +3 more
core +3 more sources
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source