Results 211 to 220 of about 15,986,900 (239)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

A multimodal adaptive optical microscope for in vivo imaging from molecules to organisms. [PDF]

Nat Methods
Fu TM, Liu G, Milkie DE, Ruan X, Görlitz F, Shi Y, Ferro V, Divekar NS, Wang W, York HM, Kilic V, Mueller M, Liang Y, Daugird TA, Gacha-Garay MJ, Larkin KA, Adikes RC, Harrison N, Shirazinejad C, Williams S, Nourse JL, Sheu SH, Gao L, Li T, Mondal C, Achour K, Hercule W, Stabley DR, Emmerich K, Dong P, Drubin DG, Liu ZJ, Mumm JS, Koyama M, Killilea AN, Bravo-Cordero JJ, Keene CD, Luo L, Kirchhausen T, Pathak MM, Arumugam S, Nuñez JK, Gao R, Matus DQ, Martin BL, Swinburne IA, Betzig E, Legant WR, Upadhyayula S.   +48 more
europepmc   +1 more source

Specialist Resource Centres as Protective Microsystems: A Qualitative Comparative Case Study of Autistic Pupils' Experiences in Mainstream Secondary Schools. [PDF]

Autism
Boddy A, Cook A.
europepmc   +1 more source

Reward Reduces Motor Fatigability by Increasing Movement Vigour

Imhof J, Heimhofer C, Bächinger M, Meissner SN, Ramsey R, Wenderoth N.   +5 more
europepmc   +1 more source

Pupil-linked arousal heterogeneously modulates cell-type-specific sensory processing. [PDF]

Sci Adv
Kaufman KJ, Krall RF, Williamson RS.
europepmc   +1 more source

The Rhythmic Embodied Perception Framework of breath, brain, and perception. [PDF]

Neurosci Conscious
Andrews R, Dockree PM.
europepmc   +1 more source

A coma pattern-based autofocusing method resolves bacterial cold shock response at single-cell level. [PDF]

Elife
Li S, Ma Z, Yu Y, Wang J, Shen Y, Cui X, Fu X, Huang S.   +7 more
europepmc   +1 more source

Critical flicker fusion frequency assessment: robustness across photopic illumination in experienced divers. [PDF]

Front Physiol
Schipke JD, Muth T, Brebeck AK, von Hertlein D, Möller FN.   +4 more
europepmc   +1 more source

Increasing carbon dioxide levels progressively modulate defensive responding across behavioural, autonomic, and neural domains

Kobakhidze N, Silvagni F, Schmuckermair C, Ebner K, Müller K, Ramos-Prats A, Ferraguti F, Singewald N, Sartori S.   +8 more
europepmc   +1 more source