Results 151 to 160 of about 29,156 (297)

Tadpole Pupil Associated With Horner\u27s Syndrome From Compression of the Carotid Sheath

open access: yes
Tadpole pupil is a rare phenomenon characterized by spontaneous segmental spasm of the iris dilator resulting in a temporarily peaked pupil shape. Pupillary distortion is usually unilateral, episodic, and can occur in any segment of the iris. Etiology of
Emily Eng; Kristina Lin; Nailyn Rasool
core  

Saccade, pupil, and blink abnormalities in prodromal and manifest alpha-synucleinopathies

open access: yes
Neurodegenerative diseases like Parkinson's disease (PD) are on the rise. In the clinic, the phenotypic similarities between early stage PD and conditions such as early-stage multiple system atrophy (MSA) complicate treatment strategies.
Timmermann, Lars   +10 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

The Teacher´s View of Pupil´s Learning Disorders

open access: yes, 2008
ANNOTATION Our thesis is focused on the problems of pupils` learning disorders at primary school. Our thesis is divided into three parts. In the theoretic one we outline problems of learning disorders, especially dysgraphia and dysorthographia.
KOLÁŘOVÁ, Martina
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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