Results 171 to 180 of about 3,239,802 (389)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Blue enriched light modulates pupil dilation induced by transcutaneous vagus nerve stimulation. [PDF]

Sci Rep
Cakiroglu I, Germany Morrison E, Brisbois S, Danthine V, Dias AM, Nonclercq A, Vandewalle G, El Tahry R.   +7 more
europepmc   +1 more source

Special educational needs and/or disabilities training toolkit : for PGCE trainees : physical and sensory impairment : developmental coordination disorder/dyspraxia : self-study task 15 [PDF]

, 2009

core  

IMPACT OF AUTISM SPECTRUM DISORDER ON THE ACADEMIC PERFORMANCE OF PRIMARY FIVE PUPILS IN BABA UMAR PRIMARY SCHOOL, AZARE, KATAGUM LOCAL. GOVERNMENT BAUCHI STATE

MUHAMMAD KAWU GABI, Nuru Gambo, Sambo M.A. Hudu Muhammad   +2 more
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Artificial Intelligence-Based Depression Detection. [PDF]

Sensors (Basel)
Kiss G, Viktor P.
europepmc   +1 more source

Training strategies specific to the physical education and sport in what concerns the social integration of pupils with special educational needs [PDF]

The training, planning and the realization of adapted physical education classes must be part of the pedagogic knowledge ensemble of the didactic frame. For every child with special educational needs it is necessary an individual approach of the training
Marin Finichiu
core   +1 more source

Children as behavior change agents: the ecological effects of a peer-mediated intervention on the problem behavior of six behavior disordered elementary school pupils

, 1990
Christopher M. P. Diachuk
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Closed-eye pupil monitoring system in patients with neurological disorders: a prospective, single-arm study [PDF]

Zhiying Shang, Shuting Chen, Ziying Hong, Bo Xu, Xiaoyan Bai, Jingyu Li, Shuang Liang, L J Zhang, Lu Chen   +8 more
openalex   +1 more source