Results 41 to 50 of about 12,481 (284)
Advanced Science, EarlyView.NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen +7 more
wiley +1 more source
HSUS Uncovers Cruel Puppy Mills [PDF]
, 1981 It is estimated that puppy mills grind out more than half a million puppies every year to be sold almost exclusively in pet stores. But it is not only puppies--who, after all, escape the squalor and crowding after six or seven weeks that suffer. Of equal
core +3 more sources
Ganglioglioma in the Thalamus of a Puppy.
Journal of Veterinary Medical Science, 2003 A solitary brain mass of a 4-month-old miniature dachshund showing seizure-like neurological signs was examined histopathologically. At necropsy a white tumor mass, replacing the thalamus, approximately 1.5 cm in diameter, was found. There was cystic space filled with yellowish pale fluid in the central area of the tumor mass.
UCHIDA, Kazuyuki +7 more
openaire +3 more sources
Advanced Science, EarlyView.Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh +22 more
wiley +1 more source
Knowledge of UK Residents About Importing Puppies from EU Countries
AnimalsThe number of puppies imported to the United Kingdom (UK) from the European Union (EU) is increasing, as are concerns about the legality, welfare and potential disease risks associated with their trade. This study aimed to use an online survey to collect
Zoe Belshaw, Rowena M. A. Packer
doaj +1 more source
Lead intoxication in a puppy - a case report
Veterinární Medicína, 2002 Lead intoxication in a puppy is described. The puppy was submitted to surgical procedure for suspicion of acute abdominal pain. Diagnosis was established on the basis of the presence of eroded lead weights in stomach, biochemical and hematological blood ...
E. Srebočan +5 more
doaj +1 more source
, 2018 Trog the cave boy has toys that should be lots of fun: sticks, rocks, and mud. But all he wants is a puppy to play with. He comes across a striped alligator and brings it home, dubbing it “Puppy!” His new pet causes a lot of problems for his family, like
Haws, Acacia
core
Advanced Science, EarlyView.The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan +10 more
wiley +1 more source
Brainstem Oligodendroglioma in a Puppy
Journal of the American Animal Hospital Association, 2013 A 5 mo old male golden retriever presented for evaluation of an acute onset, progressive neurologic disease. Although computed tomography (CT) was unremarkable, MRI identified an ill-defined mass located in the medulla, which was considered likely responsible for the clinical signs.
Mateo, Isidro +3 more
openaire +3 more sources
Advanced Science, EarlyView.SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long +12 more
wiley +1 more source