Results 41 to 50 of about 6,236 (222)

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

open access: yesAdvanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes   +15 more
wiley   +1 more source

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

open access: yesAdvanced Science, EarlyView.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li   +9 more
wiley   +1 more source

Lead intoxication in a puppy - a case report

open access: yesVeterinární Medicína, 2002
Lead intoxication in a puppy is described. The puppy was submitted to surgical procedure for suspicion of acute abdominal pain. Diagnosis was established on the basis of the presence of eroded lead weights in stomach, biochemical and hematological blood ...
E. Srebočan   +5 more
doaj   +1 more source

Brainstem Oligodendroglioma in a Puppy

open access: yesJournal of the American Animal Hospital Association, 2013
A 5 mo old male golden retriever presented for evaluation of an acute onset, progressive neurologic disease. Although computed tomography (CT) was unremarkable, MRI identified an ill-defined mass located in the medulla, which was considered likely responsible for the clinical signs.
Mateo, Isidro   +3 more
openaire   +3 more sources

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

open access: yesAdvanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen   +11 more
wiley   +1 more source

Changes in Renal Resistive Index Values in Healthy Puppies during the First Months of Life

open access: yesAnimals, 2020
The purpose of this study is to establish renal resistive index (RRI) of normal kidneys in puppies aged from newborn to 20 weeks of age and to determine the age at which RRI reaches adult dog values.
Amalia Agut   +2 more
doaj   +1 more source

Ganglioglioma in the Thalamus of a Puppy.

open access: yesJournal of Veterinary Medical Science, 2003
A solitary brain mass of a 4-month-old miniature dachshund showing seizure-like neurological signs was examined histopathologically. At necropsy a white tumor mass, replacing the thalamus, approximately 1.5 cm in diameter, was found. There was cystic space filled with yellowish pale fluid in the central area of the tumor mass.
UCHIDA, Kazuyuki   +7 more
openaire   +3 more sources

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

open access: yesAdvanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang   +27 more
wiley   +1 more source

Molecular Prevalence and Risk Factors of Campylobacter Infection in Puppies in the Nairobi Metropolitan Region, Kenya

open access: yesVeterinary Medicine International, 2023
Campylobacter species are widely distributed pathogens; however, data on its epidemiology in puppies remain scanty, especially in Kenya. A cross-sectional study was conducted in the Nairobi Metropolitan Region to determine molecular prevalence and ...
Sharon N. Mbindyo   +7 more
doaj   +1 more source

The enigma of RX Puppis [PDF]

open access: yesSymposium - International Astronomical Union, 1987
RX Puppis is a southern symbiotic star (R.A. 08h12m 28s.2, Dec. −41°33'18“ B1950). For almost a century it has been seen to have had a violent history at optical wavelengths. In 1974 it was discovered, at 5 GHz, to be a weak radio source. Shortly after, its radio spectrum was found to be of the optically thin type, having approximately the same flux ...
Alan E. Wright, David A. Allen
openaire   +1 more source

Home - About - Disclaimer - Privacy