Results 61 to 70 of about 65,463 (261)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
NILAI DAN TIPE KONSUMEN RUMAH TANGGA DAN KAITANNYA DENGAN PERILAKU PEMBELIAN PRODUK MAKANAN KEMASAN
Jurnal Ilmu Keluarga dan Konsumen, 2014 Characteristics of consumers play an important role in determining the purchasing decision process, including the value and type of consumers. The purpose of this study was to analyze the effects of values and type of households on purchasing behavior of
Ani Ruwani +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Patterns of stent purchasing in a collaborative procurement organisation [PDF]
Leveraging purchasing power through collaborative purchasing arrangements is widely used to deliver efficiency savings in public procurement.
McCabe, Joseph David James
core
The micro-macro disconnect of purchasing power parity [PDF]
The persistence of aggregate real exchange rates is a prominent puzzle, particularly since adjustment of international relative prices in microeconomic data is much faster. This paper finds that adjustment to the law of one price in disaggregated data is
Jyh-Lin Wu, Paul R. Bergin, Reuven Glick
core +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Purchasing Organization and Design: A Literature Review [PDF]
This paper presents the results of a comprehensive literature review of the organization of purchasing covering the period from 1967 to 2009. The review provides a structured overview of prior research topics and findings and identifies gaps in the ...
Christoph Glock, Simon Hochrein
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Currency Union and Real Exchange Rate Behavior [PDF]
In this paper we study the behavior of the real exchange rate of three North American currencies vis-a-vis the U.S. dollar: the Canadian dollar the Mexican peso, and the Panamanian Balboa.
James R. Lothian, Cornelia H. McCarthy
core
, 2022 Malaysia is currently stricken with Korean fever in all local industries including fashion, food and cosmetic. K-dramas, K-music, and K-culture are building a stronghold in the country with the younger generation becoming more fascinated towards South ...
Ismail, Nur Farah Mardhiah +1 more
core +1 more source