Results 101 to 110 of about 277,671 (312)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Application of Deep Learning in User Purchase Behaviour Analysis and Marketing Decision Support

International Journal of Computational Intelligence Systems
User purchase behaviour (UPB) analysis is essential in enhancing marketing strategies on e-commerce platforms. The user purchasing pattern is determined from the product analysis to procurement evaluation, directly influencing business growth.
Zhi Wang
doaj   +1 more source

Explanatory factors for the purchase of local food in a context of global environmental and economic uncertainty: An application of the stimulus-organism-response model

Cleaner and Responsible Consumption
In recent years, a growing number of consumers have become aware that they can use their purchasing behaviour to promote environmental sustainability. This trend explains the prominent role of local food purchasing and the academic attention paid to such
V. Tortosa-Edo, M.Á. Moliner Tena, F.F. Mallén Broch   +2 more
doaj   +1 more source

Exchange RAte Dynamics with Financial Repression: A Test of Exchange Rate Models for India [PDF]

This paper examines the relevance of the monetary approach for exchange rate behaviour in India, unde rthe managed float regime. It finds supprot for purchaisng power parity in traded goods and that the monetary approach provdies a reasonable description
Kenneth Kletzer, Renu Kohli
core  

Perceptions, values and behaviour: The case of organic foods [PDF]

, 2005
This analysis of the Danish organic food market investigates the relationships between household purchasing behaviour and stated values, motives and concerns. Attention is also given to the importance of sales chan-nels and the functions of labelling. We
Andersen, Laura Mørch, Millock, Katrin, O'Doherty Jensen, Katherine, Rosenkvist, Lars, Wier, Mette   +4 more
core  

The effect of prior knowledge and decision-making style on the online purchase decision-making process: A typology of consumer shopping behaviour [PDF]

, 2015
This paper provides an empirical typology of online decision-making purchasing behaviour. The study explores how the online purchase process is affected by individual decision-making style and knowledge of product.
Hollanda, Christopher P., Karimi, Sahar, Papamichail, K. Nadia   +2 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Consumers in the Circular Economy: A Path Analysis of the Underlying Factors of Purchasing Behaviour. [PDF]

Int J Environ Res Public Health, 2022
Szilagyi A, Cioca LI, Bacali L, Lakatos ES, Birgovan AL.   +4 more
europepmc   +1 more source

Purchase behaviour of children magazines

, 2021
77
openaire   +1 more source

Safety And Consumer Protection [PDF]

The purpose of this article is to analyse the connexion between rationality and emotion in shaping purchasing behaviour and the way in which some external stimuli such as expert advice or advertising influence them.
Cristina Burghelea
core