Results 61 to 70 of about 277,671 (312)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The hidden reasons behind generation Z's green choices

open access: yesDiscover Sustainability
The green purchasing decision has become an increasing research focus, reflecting consumers' growing commitment to sustainability. Generation Z consumers are recognised for their greater environmental and social awareness than other generations. Although
João M. Lopes   +3 more
doaj   +1 more source

The influence of digital marketing and social media marketing on consumer buying behavior

open access: yesJournal of Modern Science
Digital marketing and social media marketing play an essential role in shaping consumer buying behaviour. The spread of technology has created new opportunities for consumer-business interactions across various digital platforms such as social media ...
Barbara Olga Antczak
doaj   +1 more source

Role of Values and Environmental Concerns for the Sustainable Purchasing Behavior: Evidence From Pakistan [PDF]

open access: yes, 2016
Sustainable purchasing is an attempt to purchase greener, healthier, and more economical items from greener, more sustainable organizations. It is based on the idea that each and every buy has shrouded human wellbeing through natural and social effects ...
Amin, S. (Saiful)   +2 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Selected characteristics of Slovak consumers purchasing behaviour

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2008
Objective of the paper is to point out selected patterns of Slovak consumers based on analysis of buying behaviour. Results of presented survey of consumer buying patterns and preferences have poin­ted out key characteristics of buying behaviour of ...
Ľudmila Nagyová   +2 more
doaj   +1 more source

Children’s Food and Drink Purchasing Behaviour ‘‘Beyond the School Gate’’ : The Development of a Survey Module [PDF]

open access: yes, 2013
Copyright © 2013 Wendy J.Wills et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bromley, C.   +5 more
core   +4 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Encouraging Pro-Social Behavior Through Ecological Motivation and Self-Esteem

open access: yesSoutheast Asian Business Review
This research examines ecological motivation's influence on pro-social behaviour mediated by self-esteem. This research describes pro-environmental behaviour in purchasing environmentally friendly products that support issues related to the circular ...
Rini Kuswati, Gata Krisnawan
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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