Mitochondrial tRNAGlu 14687A>G May Be A Novel Mutation for Type 2 Diabetes Mellitus
We identified a novel mitochondrial tRNAGlu 14687A>G mutation in a Han Chinese pedigree with diabetes; the m.14687A>G mutation occurred at a conserved nucleotide of tRNAGlu, which was important for tRNA structure and function. Using a cybrid cell model, we found that mutant cells exhibited much more severe mitochondrial dysfunctions than control cells,
Xiaojuan Rao+3 more
wiley +1 more source
Comparative Study of Two Different Myringoplasty Techniques in Mucosal Type of Chronic Otitis Media [PDF]
Introduction: Myringoplasty is a surgical procedure used to close the perforation of pars tensa of the tympanic membrane and to improve the hearing loss.
Mallikarjunappa Ajjampura Murugendrappa+3 more
doaj +1 more source
Audiovestibular Findings in Gaucher Disease Types I and III: Evidence of Vestibular Involvement in GD1. [PDF]
ABSTRACT Gaucher disease (GD), the most prevalent lysosomal storage disorder, is characterized by varying levels of systemic and neurological involvement. This study aims to investigate audiovestibular system involvement in patients with Gaucher disease type I (GD1) and type III (GD3) using audiometric and vestibular evaluations.
Onan E+6 more
europepmc +2 more sources
Work-related noise exposure in a cohort of patients with chronic tinnitus: analysis of demographic and audiological characteristics [PDF]
Work-related noise exposure is one of the major factors contributing to the development of adult-onset hearing loss and tinnitus. The aim of this study was to analyze, in patients with chronic tinnitus and long-term occupational noise exposure, (A ...
ALTISSIMI, Giancarlo+9 more
core +2 more sources
Hearing Loss and Its Relation to Loneliness and Depression—A Population‐Based Cohort Study
This study investigated the relationship between hearing loss, loneliness, and depression using data from the Gutenberg Health Study. It found that hearing loss is significantly associated with higher levels of loneliness and depressive symptoms, with severe to complete hearing loss markedly increasing risks for loneliness and mild to severe hearing ...
Julia Döge+15 more
wiley +1 more source
Effect of noise on transient-evoked otoacoustic emissions and pure-tone screening audiometry [PDF]
Currently, the American Speech-Language Hearing Association (ASHA) recommends pure-tone audiometry as the preferred audiometric screening method of school-aged children; however, background noise is often present and can result in high referral rate. The
Wade, Laura Annette
core +1 more source
The psychophysics of absolute threshold and signal duration: A probabilistic approach [PDF]
The absolute threshold for a tone depends on its duration; longer tones have lower thresholds. This effect has traditionally been explained in terms of ?temporal integration? involving the summation of energy or perceptual information over time.
Heil P.+5 more
core +1 more source
Tactile responses in pure-tone audiometry: a saccule function? [PDF]
As generally accepted, low-frequency bone-conduction thresholds obtained in the 35–55 dB range are often tactile responses and not due to auditory stimulation [4]. Since it is recently known that low-frequency airand bone-conducted stimuli can be used to test otolithic function also in humans [2], we wondered if such ‘‘false-positive’’ boneconduction ...
Julia Louza+4 more
openaire +3 more sources
While both cochlear implants and bone conduction implants improve tinnitus symptoms, cochlear implants provide significantly greater suppression across multiple tinnitus severity measures and a higher cure rate, positioning it as the preferred option for tinnitus management in asymmetric hearing loss and single‐sided deafness patients.
Jae Sang Han+5 more
wiley +1 more source
Objective. The aim of this study is to analyze the high-frequency hearing levels in patients with rheumatoid arthritis and to determine the relationship between hearing loss, disease duration, and immunological parameters. Materials and Methods.
Mar Lasso de la Vega+3 more
doaj +1 more source