Renal Transplantation in Pure Autonomic Failure [PDF]
We report the case of a 69-y-old gentleman with PAF who developed end-stage renal disease necessitating peritoneal disease (PD) and transplantation.
Zain Ul Abideen, MRCP, UK+5 more
doaj +6 more sources
Pure Autonomic Failure: A Case Report of Recurrent Orthostatic Hypotension [PDF]
Pure autonomic failure is a neurodegenerative disorder affecting the autonomic nervous system which clinically presents with orthostatic hypotension. It is a diagnosis of exclusion after detailed clinical examinations and relevant investigations.
Prabin Khatri+9 more
doaj +8 more sources
Cardiac sympathetic innervation and vesicular storage in pure autonomic failure [PDF]
Objective Pure autonomic failure (PAF) is a rare disease characterized by neurogenic orthostatic hypotension (nOH), absence of signs of central neurodegeneration, and profound deficiency of the sympathetic neurotransmitter norepinephrine.
David S. Goldstein+4 more
doaj +8 more sources
A Case of Pure Autonomic Failure Initially Presenting with Hemihypohidrosis: Twelve-Year Follow-Up [PDF]
Although it is generally recognized that pure autonomic failure (PAF) is a progressive neurodegenerative disease selectively involving the autonomic nervous system, its mode of progression remains to be settled.
Hiroshi Saito
doaj +5 more sources
Pelvic autonomic dysfunction is common in patients with pure autonomic failure. [PDF]
AbstractBackground and PurposePure autonomic failure (PAF) presents primarily as cardiovascular autonomic failure and may phenoconvert to other neurodegenerative disorders. However, the involvement of other autonomic functions has been poorly evaluated.
Vichayanrat E+5 more
europepmc +5 more sources
Relationships Between Cardiovascular Autonomic Profile and Work Ability in Patients With Pure Autonomic Failure [PDF]
Pure autonomic failure (PAF) is a rare disorder belonging to the group of synucleinopathies, characterized by autonomic nervous system degeneration.
Antonio R. Zamunér+12 more
doaj +5 more sources
Predicting phenoconversion in pure autonomic failure. [PDF]
To determine predicting factors and frequency of phenoconversion from pure autonomic failure (PAF) into a synucleinopathy with motor or cognitive involvement of multiple system atrophy (MSA), Parkinson disease (PD), or dementia with Lewy bodies (DLB).We performed a retrospective review of all patients with PAF from 2001 to 2011 evaluated at Mayo Clinic,
Coon EA+6 more
europepmc +7 more sources
Abnormal dopamine transporter imaging in pure autonomic failure: a potential biomarker of central nervous system involvement. [PDF]
Pure autonomic failure (PAF) is a rare progressive neurodegenerative disease characterized by neurogenic orthostatic hypotension at presentation, without other neurological abnormalities.
Alnasser Alsukhni R+10 more
europepmc +4 more sources
Pure Autonomic Failure-A Localized Alpha Synucleinopathy with a Potential for Conversion to More Extensive Alpha Synucleinopathies. [PDF]
Pure autonomic failure (PAF) is an alpha synucleinopathy with predominant involvement of the autonomic ganglia and peripheral nerves. The hallmark clinical feature is orthostatic hypotension.
Bhattacharjee S, Alsukhni RA.
europepmc +3 more sources
Autonomic ganglionic injection of α-synuclein fibrils as a model of pure autonomic failure α-synucleinopathy [PDF]
Autonomic dysfunction is a feature of some α-synucleinopathies, but there are no models of pure autonomic dysfunction associated with α-synuclein.
Xue-Jing Wang+10 more
doaj +3 more sources