Results 21 to 30 of about 7,102 (233)
Report of an early case of Shy-Drager syndrome in a 67 year-old woman patient. Autonomic failure was diagnosed by functional evaluation as well as laboratory tests. MR imaging disclosed a prominent putamina hypodensity in T2-weighted images at high field
Jayme A. Maciel Jr. +3 more
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Parkinson’s disease (PD) is a neurodegenerative disease with a 200 year-long research history. Our understanding about its clinical phenotype and pathogenesis remains limited, although dopaminergic replacement therapy has significantly improved patient ...
Zhichun Chen, Guanglu Li, Jun Liu
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Passive Immunization in Alpha-Synuclein Preclinical Animal Models
Alpha-synucleinopathies include Parkinson’s disease, dementia with Lewy bodies, pure autonomic failure and multiple system atrophy. These are all progressive neurodegenerative diseases that are characterized by pathological misfolding and accumulation of
Jonas Folke +4 more
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Congenital Insensitivity to Pain (HSNA type IV)
Investigators from New York University, NY, studied 14 patients with congenital insensitivity to pain with anhidrosis (CIPA), compared to 10 patients with chronically deficient sympathetic activity (pure autonomic failure), and 15 normal age-matched ...
J Gordon Millichap
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Background Orthostatic hypotension (OH) in geriatric patients frequently involves a component of autonomic failure (AF). The combination of OH with nocturnal hypertension (NHT) is indicative of AF, which is described as pure (PAF), when neurologic ...
Siddhartha Lieten +3 more
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Background Discerning the mechanisms driving orthostatic symptoms in human beings remains challenging. Therefore, we developed a novel approach combining cardiac and cerebral real‐time magnetic resonance imaging, beat‐to‐beat physiological monitoring ...
Darius A. Gerlach +10 more
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Background: Supine hypertension, a consequence of autonomic neuropathy, is a rarely recognized pathological condition. Reported diseases in the background are pure autonomic failure, multiple system atrophy, Parkinson’s disease, diabetes and different ...
Dóra Batta +2 more
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Hormonal and cardiovascular reflex assessment in a female patient with pure autonomic failure
We report the case of a 72-year-old female with pure autonomic failure, a rare entity, whose diagnosis of autonomic dysfunction was determined with a series of complementary tests.
Heno Ferreira Lopes +5 more
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We present the case of a 64-year-old woman who, in the past 5 years, complained of constipation/diarrhea, hyposudoresis, xerostomia and xerophthalmia, dysuria and orthostatic hypotension.
J L Ducla-Soares +8 more
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Hemodynamic Effects of the Osmopressor Response: A Systematic Review and Meta‐Analysis
Background Rapidly consuming water may offer practical orthostatic hypotension therapy. However, its efficacy across disorders remains uncertain. This study aims to assess the impact of rapid 350‐ to 500‐mL water intake on systolic and diastolic blood ...
Oyebimbola A. Oyewunmi +5 more
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