Results 31 to 40 of about 25,785 (225)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
On the grade of modules over Noetherian rings
, 2007 Let $\Lambda$ be a left and right noetherian ring and $\mod \Lambda$ the category of finitely generated left $\Lambda$-modules. In this paper we show the following results: (1) For a positive integer $k$, the condition that the subcategory of $\mod ...
Huang, Zhaoyong
core +2 more sources
On finitely injective modules and locally pure-injective modules over Prüfer domains [PDF]
Proceedings of the American Mathematical Society, 2007 Let \(R\) be a ring. An \(R\)-module \(M\) is said to be finitely injective if every finite set of elements of \(M\) is contained in an injective submodules; and is said to be locally pure-injective if every element \(x \in M\) belongs to a pure-injective summand of \(M\).
openaire +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Modules with irrational slope over tubular algebras
, 2014 Let $A$ be a tubular algebra and let $r$ be a positive irrational. Let ${\mathcal D}_r$ be the definable subcategory of $A$-modules of slope $r$. Then the width of the lattice of pp formulas for ${\mathcal D}_r$ is $\infty$.
Harland, Richard, Prest, Mike
core +1 more source
Σ-pure-injective modules for string algebras and linear relations [PDF]
Journal of Algebra, 2018 We prove that indecomposable $ $-pure-injective modules for a string algebra are string or band modules. The key step in our proof is a splitting result for infinite-dimensional linear relations.
Raphael Bennett-Tennenhaus +1 more
openaire +4 more sources
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Right orthogonal class of pure projective modules over pure hereditary rings
, 2020 Let $\mathcal{W}$ be the class of all pure projective modules. In this article, $\mathcal{W}$-injective modules is defined via the vanishing of cohomology of pure projective modules.
Arunachalam, Umamaheswaran +1 more
core
Modules with cosupport and injective functors [PDF]
, 2008 Several authors have studied the filtered colimit closure lim(B) of a class B of finitely presented modules. Lenzing called lim(B) the category of modules with support in B, and proved that it is equivalent to the category of flat objects in the functor ...
Holm, Henrik
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source