Results 231 to 240 of about 3,264,899 (354)

A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals

Advanced Science, EarlyView.
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang, Xue‐Jing Lu, Hui‐Juan Zhang, Zhao‐Xing Wei, Ya‐Zhuo Kong, Yi‐Heng Tu, Gian Domenico Iannetti, Li Hu   +7 more
wiley   +1 more source

Diagnostics of diabetic retinopathy based on fundus photos using machine learning methods with advanced feature engineering algorithms. [PDF]

Sci Rep
Gandor M, Pałka F, Książek W, Pławiak P, Siedlecka A, Jeruzalski T, Olender-Skorek M, Jonak K, Rejdak R, Nowomiejska K, Matysik-Woźniak A, Teus M, Sanchez CA, Sylwestrzak M.   +13 more
europepmc   +1 more source

AI‐Driven De Novo Design of Ultra Long‐Acting GLP‐1 Receptor Agonists

Advanced Science, EarlyView.
De novo GLP‐1RAs can be computationally designed to exhibit extended half‐life and superior efficacy compared to Semaglutide. Abstract Peptide drugs have revolutionized modern therapeutics, offering novel treatment avenues for various diseases. Nevertheless, low design efficacy, time consumption, and high cost still hinder peptide drug design and ...
Ting Wei, Jiating Ma, Xiaochen Cui, Jiahui Lin, Zhuoqi Zheng, Liu Cheng, Taiying Cui, Xiaoqian Lin, Junjie Zhu, Xuyang Ran, Xiaokun Hong, Luke Johnston, Zhangsheng Yu, Haifeng Chen   +13 more
wiley   +1 more source

Prediction of suitable drug for keloid through analytic hierarchy process and topological indices. [PDF]

Sci Rep
Janagi K, Usha A, Ismail R, Shanmukha MC.   +3 more
europepmc   +1 more source

Benchmarking Ploidy Estimation Methods for Bulk and Single‐Cell Whole Genome Sequencing

Advanced Science, EarlyView.
It comprehensively benchmarks computational tools for ploidy estimation from bulk and single‐cell whole‐genome sequencing data. The results highlight the strengths and limitations of each method under different conditions and identify PURPLE and SeCNV show top performance in bulk and single‐cell settings, respectively.
Yawei Song, Zilv Mei, Qijie Zheng, Qingqing Yuan, Yu Liang, Jiaqi Gao, Lang Zhou, Shuheng Wu, Wei Wu   +8 more
wiley   +1 more source

A Novel 2-DOF PIDA control strategy with GCRA-based parameter optimization for electric furnace temperature control. [PDF]

PLoS One
Eker E, Izci D, Ekinci S, Elsayed F, Salman M.   +4 more
europepmc   +1 more source

Next‐Generation Piezoelectric Materials in Wearable and Implantable Devices for Continuous Physiological Monitoring

Advanced Science, EarlyView.
An analysis of literature trends and a historical overview of organic and inorganic piezoelectric materials, focusing on their structural diversity, functional mechanisms, and inherent characteristics. It then explores cutting‐edge developments in material synthesis, fabrication processes, and performance optimization, highlighting their applicability ...
Bangul Khan, Umay Amara, Bilawal Khan, Wasim Ullah Khan, Rafi u Shan Ahmad, Muhammad Shehzad Khan, Mohamed Elhousseini Hilal, Bee Luan Khoo   +7 more
wiley   +1 more source

Advection, diffusion and linear transport in a single path-sampling Monte-Carlo algorithm: Getting insensitive to geometrical refinement. [PDF]

PLoS One
Ibarrart L, Blanco S, Caliot C, Dauchet J, Eibner S, El Hafi M, Farges O, Forest V, Fournier R, Gautrais J, Konduru R, Penazzi L, Trégan JM, Vourc'h T, Yaacoub D.   +14 more
europepmc   +1 more source

Flexible Memory Application of Nanoscale Ti–Ge–Te Thin Film as Information Storage Medium With Excellent Thermal Stability, Low Resistance Drift and Superior Bending Characteristic

Advanced Science, EarlyView.
Nanoscale Ti–Ge–Te films were fabricated via magnetron co‐sputtering, exhibiting the exceptional thermal stability, low resistance drift, and superior mechanical flexibility. Density functional theory reveals Ti doping can convert GeTe to a direct bandgap semiconductor and enhance covalent Ti–Te bonding. Flexible phase‐change memory devices demonstrate
Han Gu, Weihua Wu, Xiaochen Zhou, Pei Zhang, Bowen Fu, Jiwei Zhai, Sannian Song, Zhitang Song   +7 more
wiley   +1 more source

Evolution of cooperation guided by the coexistence of imitation learning and reinforcement learning. [PDF]

Sci Rep
Tang W, Wang G, Xing Z.
europepmc   +1 more source