Results 141 to 150 of about 1,815,431 (234)

Rapid affinity-based purification of multi-specific antibodies using Kappa Select and Protein L. [PDF]

MAbs
Mix K, Sun T, Hall B, Newton J, Eng C, Guo Y, Reczek D.   +6 more
europepmc   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Application of aqueous biphasic systems based on pluronic copolymer and deep eutectic solvent to achieve purified C phycocyanin. [PDF]

Sci Rep
Ebrahimi A, Pazuki G, Mozaffarian M, Ahsaie FG, Abedini H.   +4 more
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Optimization of methods for isolation and purification of outer membrane vesicles (OMVs) from Neisseria lactamica. [PDF]

Appl Microbiol Biotechnol
Preto RM, Dos Santos VCT, Lordelo MVS, Pereira GHF, Leite LCC, Gonçalves VM, Barazzone GC.   +6 more
europepmc   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Synthesis of polyaniline zirconium for purification of barberry anthocyanins and stabilization via copigmentation against thermal and gastrointestinal conditions. [PDF]

Sci Rep
Dara A, Feizy J, Naji-Tabasi S, Fooladi E, Rafe A.   +4 more
europepmc   +1 more source

The purification of ergosterol [PDF]

Biochemical Journal, 1931
openaire   +3 more sources

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

FEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei, Amir Barzegar Behrooz, Marco Cordani, Mahmoud Aghaei, Negar Azarpira, Daniel J. Klionsky, Saeid Ghavami   +6 more
wiley   +1 more source

Clinical analysis of acute pancreatitis after kidney transplantation: a single-center retrospective observational study. [PDF]

BMC Gastroenterol
Yang M, Li Y, Zhao H, Xiao D, Zhou Q, Qin W, Xu X.   +6 more
europepmc   +1 more source