The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
Development of an Industry-Applicable Distillation Process to Prepare High-Purity Furfural. [PDF]
Cai W, Wang Z, Yang GQ, Qian J.
europepmc +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Construction of Biaryl Sulfonamides via Pd(II)-Catalyzed Cross-Coupling of C(sp<sup>2</sup>)-H Bonds with Iodobenzenesulfonamides. [PDF]
Bhattacharya D+3 more
europepmc +1 more source
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki+11 more
wiley +1 more source
Co-purification of the GroEL chaperone during outer membrane vesicle purification: insights from <i>Aeromonas salmonicida</i> subsp. <i>salmonicida</i>. [PDF]
Paquet MF, Charette SJ.
europepmc +1 more source
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley +1 more source
Novel processes to obtain pneumococcal surface proteins for vaccines. [PDF]
Gonçalves VM.
europepmc +1 more source
A review of artificial intelligence in brachytherapy
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen+4 more
wiley +1 more source
Purification of Low-Complexity Domain Proteins FUS, EWSR1, and Their Fusions. [PDF]
Altemus JJ+3 more
europepmc +1 more source