Results 301 to 310 of about 1,394,357 (370)

Interaction of Tri-Cyclic Nucleobase Analogs with Enzymes of Purine Metabolism: Xanthine Oxidase and Purine Nucleoside Phosphorylase. [PDF]

Int J Mol Sci
Stachelska-Wierzchowska A, Narczyk M, Wierzchowski J, Bzowska A, Wielgus-Kutrowska B.   +4 more
europepmc   +1 more source

Metabolism‐Regulating Nanomedicines for Cancer Therapy

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression. [PDF]

Cancer Res Commun
Tangudu NK, Buj R, Wang H, Wang J, Cole AR, Uboveja A, Fang R, Amalric A, Yang B, Chatoff A, Crispim CV, Sajjakulnukit P, Lyons MA, Cooper K, Hempel N, Lyssiotis CA, Chandran UR, Snyder NW, Aird KM.   +18 more
europepmc   +1 more source

STUDIES OF PURINE METABOLISM

Cold Spring Harbor Symposia on Quantitative Biology, 1948
openaire   +1 more source

Utilizing an integrated bioinformatics and machine learning approach to uncover biomarkers linking ulcerative colitis to purine metabolism-related genes. [PDF]

Heliyon
Chen T, Tao Y, Wang Q, Pei Y, Zhao Z, Yang W, Lu Y.   +6 more
europepmc   +1 more source

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A Photoactivated Sorafenib-Ruthenium(II) Prodrug for Resistant Hepatocellular Carcinoma Therapy through Ferroptosis and Purine Metabolism Disruption.

Journal of Medicinal Chemistry, 2022
The curative effect of sorafenib in hepatocellular carcinoma (HCC) is limited and sorafenib resistance remains a major obstacle for HCC. To overcome this obstacle, a new photoactive sorafenib-Ru(II) complex Ru-Sora has been designed. Upon irradiation (λ =
Yidan Lai, Nong Lu, Shuangling Luo, Haobing Wang, Pingyu Zhang   +4 more
semanticscholar   +1 more source