Results 171 to 180 of about 27,209 (247)

In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase

Cancer Chemotherapy and Pharmacology, 2012
E. Sorscher, J. Hong, P. Allan, W. Waud, W. Parker   +4 more
semanticscholar   +1 more source

An unusual presentation of purine nucleoside phosphorylase deficiency mimicking systemic juvenile idiopathic arthritis complicated by macrophage activation syndrome. [PDF]

Pediatr Rheumatol Online J, 2019
Arduini A, Marasco E, Marucci G, Pardeo M, Insalaco A, Caiello I, Moneta GM, Prencipe G, De Benedetti F, Bracaglia C.   +9 more
europepmc   +1 more source

Ringversuch zu radioimmunologischen Thyrotropinbestimmung (hTSH) im Serum [PDF]

, 1976
Erhardt, F., Marschner, I., Scriba, Peter Christian   +2 more
core  

Use of E. coli Purine Nucleoside Phosphorylase in the Treatment of Solid Tumors. [PDF]

Curr Pharm Des, 2017
Parker WB, Sorscher EJ.
europepmc   +1 more source

Erster Ringversuch zur Bestimmung der Konzentrationen von L-trijodthyronin (T3) und L-Thyroxin (T4) im Serum [PDF]

, 1976
Horn, K., Marschner, I., Scriba, Peter Christian   +2 more
core  

Metabolic and genetic factors affecting the productivity of pyrimidine nucleoside in [PDF]

core   +1 more source

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Symmetric Nucleosides as Potent Purine Nucleoside Phosphorylase Inhibitors

The Journal of Physical Chemistry B, 2021
Nucleic acids are one of the most enigmatic biomolecules crucial to several biological processes. Nucleic acid-protein interactions are vital for the coordinated and controlled functioning of a cell, leading to the design of several nucleoside/nucleotide analogues capable of mimicking these interactions and hold paramount importance in the field of ...
Pradeep Pant, Amita Pathak, B. Jayaram
openaire   +3 more sources

Combined immunodeficiency due to purine nucleoside phosphorylase deficiency: Outcome of three patients.

European Journal of Medical Genetics, 2022
Purine nucleoside phosphorylase (PNP) is a key enzyme in the purine salvage pathway. PNP deficiency, caused by the autosomal recessive mutations in the PNP gene, can lead to severe combined immunodeficiency (SCID).
Basak Torun, A. Bilgin, D. Orhan, R. Gocmen, Ş. Kılıç, B. Kuşkonmaz, D. Çetinkaya, I. Tezcan, D. Çağdaş   +8 more
semanticscholar   +1 more source

LINGCOD MUSCLE PURINE NUCLEOSIDE PHOSPHORYLASE

Canadian Journal of Biochemistry and Physiology, 1958
A purine nucleoside phosphorylase enzyme preparation, which catalyzed the general reaction ribose (deoxyribose) [Formula: see text] nucleoside (deoxynucleoside)+orthophosphate, was isolated from muscles of the lingcod (Ophiodon elongatus). The reaction was found to be about 85% in favor of nucleoside synthesis with 10 μM./ml.
openaire   +2 more sources

Purine nucleoside phosphorylase of chicken liver

Biochimica et Biophysica Acta (BBA) - Enzymology, 1971
Abstract Purine nucleoside phosphorylase (purine nucleoside:orthophosphate ribosyltransferase, EC 2.4.2.1) has been purified 125-fold from the homogenate of chicken livers and some of the properties of the purified enzyme have been studied. This enzyme had a pH optimum at around 6.o. At high substrate levels of inosine the reaction rate was increased,
K, Murakami, A, Mitsui, K, Tsushima
openaire   +2 more sources