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16 Purine Nucleoside Phosphorylase

1972
Publisher Summary This chapter focuses on purine nucleoside phosphorylases (PNPases), which are widely distributed in nature and have been identified and studied in a number of tissues in mammals, chickens, fish, yeast, and in several species of bacteria. In the erythrocytes of dogs, the activity of PNPase is remarkably low when compared with the red
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Chapter 3. Purine Nucleoside Phosphorylase

2007
Purine nucleoside phosphorylase (PNP) catalyzes the reversible phosphorolysis of purine ribonucleosides and 2′-deoxypurine ribonucleosides to the free base, and ribose 1-phosphate or 2′-deoxyribose 1-phosphate, respectively.1–3 PNPs are found in most prokaryotic and eukaryotic organisms where the en...
Yang Zhang, Steven E. Ealick
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Purine nucleoside phosphorylase deficiency.

Immunodeficiency reviews, 1991
Purine nucleoside phosphorylase (PNP) deficiency is a rare inherited disease accounting for approximately 4% of patients with severe combined immunodeficiency. Thirty-three patients have been reported. PNP-deficient patients suffer from recurrent infections, usually beginning in the first year of life. Two thirds of patients have evidence of neurologic
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Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro‐inflammatory stimulation with extracellular ATP via P2X7 receptors

Neurochemistry International, 2017
Luis Emiliano Peña-Altamira, E. Polazzi, P. Giuliani, A. Beraudi, F. Massenzio, Ilaria Mengoni, A. Poli, M. Zuccarini, R. Ciccarelli, P. Di Iorio, M. Virgili, Barbara Monti, F. Caciagli   +12 more
semanticscholar   +1 more source

Thyroid purine nucleoside phosphorylase

Biochimica et Biophysica Acta (BBA) - Enzymology, 1979
Jeffrey D. Carlson, Allan G. Fischer
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Structural characterization of purine nucleoside phosphorylase from human pathogen Helicobacter pylori.

International Journal of Biological Macromolecules, 2017
Z. Štefanić, Goran Mikleušević, M. Luić, A. Bzowska, Ivana Leščić Ašler   +4 more
semanticscholar   +1 more source

Purine Nucleoside Phosphorylase

1985
Johanna D. Stoeckler, Robert E. Parks
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Purine-nucleoside phosphorylase

1996
Dietmar Schomburg, Dörte Stephan
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Purine Nucleoside Phosphorylase Deficiency

2022
Michael Tsui, Eyal Grunebaum
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Development of a new HPLC method using fluorescence detection without derivatization for determining purine nucleoside phosphorylase activity in human plasma.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016
P. Giuliani, M. Zuccarini, S. Buccella, Margherita Rossini, I. D'alimonte, R. Ciccarelli, M. Marzo, A. Marzo, P. Di Iorio, F. Caciagli   +9 more
semanticscholar   +1 more source