Results 101 to 110 of about 1,131,346 (296)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

THE IMPACT OF CULTURE ON HEALTHCARE SEEKING BEHAVIOUR OF KALDERASH ROMA. A QUALITATIVE DESCRIPTIVE STUDY [PDF]

open access: yesDiversitate si Identitate Culturala in Europa, 2012
Some ethnic groups, as the Roma, are thought to have different healthcare seeking behaviour. This paper aims to provide findings on the attitudes, preferences, expectations and concerns of a Roma ethnic group (Kalderash) regarding inpatient ...
Gabriel ROMAN   +2 more
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Purity and impurity : written especially for giving to lads of 15 years and upwards who are going out into the world.

open access: yes, 1900
"Australasian White Cross League"--Cover.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.aus-vn4401562.Purity and impurity : a booklet for ...

core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Modeling of Self-Aligned Selector Based on Ultra-Thin Metal Oxide for Resistive Random-Access Memory (RRAM) Crossbar Arrays

open access: yesNanomaterials
Resistive random-access memory (RRAM) is a crucial element for next-generation large-scale memory arrays, analogue neuromorphic computing and energy-efficient System-on-Chip applications.
Mikhail Fedotov   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Purification of industrial grade lithium chloride for the recovery of high purity battery grade lithium carbonate

open access: yesSeparation and Purification Technology, 2019
Due to lithium’s high energy along with other exceptional characteristics, lithium demand across many industries is rising, specifically for Li-batteries.
Nick Linneen, R. Bhave, D. Woerner
semanticscholar   +1 more source

TRIzol-based RNA Extraction: A Reliable Method for Gene Expression Studies [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2014
RNA extraction is a prerequisite technique for gene expression studies, analyzing the etiology and disease progression, treatment effects, as well as designing the diagnostic methods.
M. Pahlevan Kakhki
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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