Results 91 to 100 of about 1,131,346 (296)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Discrepancies in Composition and Biological Effects of Different Formulations of Chondroitin Sulfate

open access: yesMolecules, 2015
Osteoarthritis is a common, progressive joint disease, and treatments generally aim for symptomatic improvement. However, SYmptomatic Slow-Acting Drugs in Osteoarthritis (SYSADOAs) not only reduce joint pain, but slow structural disease progression.
Johanne Martel-Pelletier   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Determination of Weed Seeds Mixed with Wheat Product in Diyarbakır

open access: yesTürkiye Tarımsal Araştırmalar Dergisi, 2018
This research was performed to determine the weed seeds that are mixed into the harvested wheat crop in Diyarbakir in 2017. For this purpose, 100 samples were taken from wheat products on 10 provinces wheat cultivated intensively.
Fırat PALA   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Production of High Purity Amorphous Silica from Rice Husk

open access: yes, 2016
Combustion of the rice husk produces rice husk ash, which consists of mainly silica. High purity silica can be produced by controlled combustion after acid treatment.
R. A. Bakar, R. Yahya, S. Gan
semanticscholar   +1 more source

High-Purity Water System Design

open access: yes, 2017
Presented on February 23, 2017 in the Marcus Nanotechnology Building, Room 1117, Georgia Tech.Introduction to High-Purity Water Standards : Implications for System Design and OperationSession 3: High-Purity Water System Design; Unit Operations ...
Sundstrom, Glen
core  

Supercritical Fluid Extraction of Lutein from Scenedesmus almeriensis

open access: yesMolecules, 2019
Lutein has several benefits for human health, playing an important role in the prevention of age-related macular degeneration (AMD), cataracts, amelioration of the first stages of atherosclerosis, and some types of cancer.
Sanjeet Mehariya   +10 more
doaj   +1 more source

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