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Purkinje Cells and their Responses
1967In Chapter I there is an extensive account of the structural features of the most remarkable elements of the cerebellar cortex, the Purkinje cells, and in Chapter III there is a full description of the synapses that parallel fibers make with the spiny branchlets of Purkinje cell dendrites.
John C. Eccles +2 more
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Axonal abnormalities in cerebellar Purkinje cells of the ?hyperspiny Purkinje cell? mutant mouse
Journal of Neurocytology, 1990The hyperspiny Purkinje cell (hpc) is a murine, autosomal recessive mutation affecting cerebellar Purkinje cells. Axonal abnormalities in these neurons have been revealed by selective silver impregnation, specific immunohistochemical staining and electron microscopy.
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Cell Counts of Purkinje and Inferior Olivary Neurons in the ‘Hyperspiny Purkinje Cells’ Mutant Mouse
European Journal of Neuroscience, 1992AbstractThe mutant mouse ‘hyperspiny Purkinje cells’(hpc) has morphologically abnormal Purkinje cells and below normal intracerebellar calbindin‐D28k, a calcium‐binding protein that, in the cerebellum, is found only in the Purkinje cells. We counted the Purkinje cells on serial sections stained with thionin or labelled with anti‐calbindin‐D28k ...
F., Frederic +5 more
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A computer model of cerebellar purkinje cells
Neuroscience, 1977Abstract A mathematical computer model of frog Purkinje cells is generated on the basis of presentday morphological and physiological data. The model utilizes passive cable equations and the Hodgkin & Huxley equations describing ionic conductances in excitable membranes.
A, Pellionisz, R, Llinás
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Purkinje cell activation by stimulation of the labyrinth
Pfl�gers Archiv European Journal of Physiology, 1970Caloric and galvanic stimulation of the labyrinth can modulate the activity of the Purkinje cells of the cerebellum through both mossy fibre and climbing fibre systems. The former system is modulated in a higher frequency range than the latter. These results were obtained mainly in the vestibular area, but they were also present in other areas of the ...
M, Ferin, R A, Grigorian, P, Strata
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Neuroscience Gateway, 2006
Compromised glutamate transport in Bergmann glia contributes to Purkinje cell death in a model of spinal cerebellar ataxia.
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Compromised glutamate transport in Bergmann glia contributes to Purkinje cell death in a model of spinal cerebellar ataxia.
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1992
We present a mathematical/computer model of a Purkinje cell. The model is a binary dendritic tree of Rall compartments connected to trunk, soma and then Hodgkin-Huxley axon. We perform studies of the model for different parameters, especially those provided by Shelton, and Pellionisz and Linas.
E. K. Blum, Xin Wang
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We present a mathematical/computer model of a Purkinje cell. The model is a binary dendritic tree of Rall compartments connected to trunk, soma and then Hodgkin-Huxley axon. We perform studies of the model for different parameters, especially those provided by Shelton, and Pellionisz and Linas.
E. K. Blum, Xin Wang
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Heterotopic Purkinje cells in ataxia‐telangiectasia
Neuropathology, 2011Ataxia‐telangiectasia (A‐T) is a heritable disorder of cerebellar ataxia and oculocutaneous telangiectasias caused by mutation of the ATM gene. The most prominent and consistent neuropathologic finding in the disorder is cerebellar cortical degeneration involving significant loss of granule and Purkinje cells.
Alexander R, Bottini +3 more
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Gravity responses of Purkinje cells in the nodulus
Experimental Brain Research, 1976In cats, either decerebrated or under chloralose anaesthesia, Purkinje cells (P-cells) of the cerebellar nodulus have been examined with the animal under static lateral tilt (roll +/- 20 degrees). The cell activity was extracellularly recorded and both "simple" and "complex" spike discharge patterns were studied. In 20 cells out of a population of 198,
G, Marini, L, Provini, A, Rosina
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Patterned Purkinje cell death in the cerebellum
Progress in Neurobiology, 2003The object of this review is to assemble much of the literature concerning Purkinje cell death in cerebellar pathology and to relate this to what is now known about the complex topography of the cerebellar cortex. A brief introduction to Purkinje cells, and their regionalization is provided, and then the data on Purkinje cell death in mouse models and,
Justyna R, Sarna, Richard, Hawkes
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