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The human Purkinje cells

Acta Neuropathologica, 1982
Purkinje cells from five autopsy cases (a premature newborn infant, a GM1-gangliosidosis, an olivo-ponto-cerebellar atrophy, a multisystem atrophy involving the spinal cord and the brain stem, and a woman of 82 years) were studied using the Golgi impregnation technique.
K, Fujisawa, A, Nakamura
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Purkinje Cell Transplants inShakerMutant Rats with Hereditary Purkinje Cell Degeneration and Ataxia

Experimental Neurology, 1998
Shaker mutant rats are characterized by the adult-onset degeneration of cerebellar anterior lobe Purkinje cells and temporally correlated development of ataxia and tremor. Normal E-13 Purkinje cells were transplanted into the anterior cerebellum in adult shaker mutant rats to study donor/host interactions in an animal with adult-onset ...
D L, Tolbert, J, Heckroth
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Axonal abnormalities in cerebellar Purkinje cells of the ?hyperspiny Purkinje cell? mutant mouse

Journal of Neurocytology, 1990
The hyperspiny Purkinje cell (hpc) is a murine, autosomal recessive mutation affecting cerebellar Purkinje cells. Axonal abnormalities in these neurons have been revealed by selective silver impregnation, specific immunohistochemical staining and electron microscopy.
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Cell Counts of Purkinje and Inferior Olivary Neurons in the ‘Hyperspiny Purkinje Cells’ Mutant Mouse

European Journal of Neuroscience, 1992
AbstractThe mutant mouse ‘hyperspiny Purkinje cells’(hpc) has morphologically abnormal Purkinje cells and below normal intracerebellar calbindin‐D28k, a calcium‐binding protein that, in the cerebellum, is found only in the Purkinje cells. We counted the Purkinje cells on serial sections stained with thionin or labelled with anti‐calbindin‐D28k ...
F., Frederic   +5 more
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The Purkinje Cell

2000
Abstract Jan Evangelista Purkinje (Purkyne) was born in 1787, in the castle of Libochovice, Bohemia, where his father acted as the estate manager. He received his first formal education at the Gymnasium connected to the monastery of the Fratres piarum scholarum, in Mikulov, South Moravia, and later joined this order. After completing his
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Purkinje cell activation by stimulation of the labyrinth

Pfl�gers Archiv European Journal of Physiology, 1970
Caloric and galvanic stimulation of the labyrinth can modulate the activity of the Purkinje cells of the cerebellum through both mossy fibre and climbing fibre systems. The former system is modulated in a higher frequency range than the latter. These results were obtained mainly in the vestibular area, but they were also present in other areas of the ...
M, Ferin, R A, Grigorian, P, Strata
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Heterotopic Purkinje cells in ataxia‐telangiectasia

Neuropathology, 2011
Ataxia‐telangiectasia (A‐T) is a heritable disorder of cerebellar ataxia and oculocutaneous telangiectasias caused by mutation of the ATM gene. The most prominent and consistent neuropathologic finding in the disorder is cerebellar cortical degeneration involving significant loss of granule and Purkinje cells.
Alexander R, Bottini   +3 more
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Design for Purkinje Cells

1992
We present a mathematical/computer model of a Purkinje cell. The model is a binary dendritic tree of Rall compartments connected to trunk, soma and then Hodgkin-Huxley axon. We perform studies of the model for different parameters, especially those provided by Shelton, and Pellionisz and Linas.
E. K. Blum, Xin Wang
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Patterned Purkinje cell death in the cerebellum

Progress in Neurobiology, 2003
The object of this review is to assemble much of the literature concerning Purkinje cell death in cerebellar pathology and to relate this to what is now known about the complex topography of the cerebellar cortex. A brief introduction to Purkinje cells, and their regionalization is provided, and then the data on Purkinje cell death in mouse models and,
Justyna R, Sarna, Richard, Hawkes
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Selective sensitivity of the Purkinje cells of the cerebellum

The American Journal of Medicine, 1954
Abstract A non-progressive parenchymatous cerebellar syndrome following abruptly upon an episode of hyperpyrexia is described. The relevant literature is reviewed and the syndrome is differentiated from progressive parenchymatous cerebellar degeneration.
D A, FREEDMAN, J C, ROURKE
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